N-Benzyl-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine

Base Information

Chemical Name:N-Benzyl-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine
CAS No.:218924-74-4
Molecular Formula:C₂₅H₂₆N₆O₅
Molecular Weight:490.519
Hs Code.:
DSSTox Substance ID:DTXSID201175985
Nikkaji Number:J1.042.165I
ChEMBL ID:CHEMBL3143238

Synonyms:CHEMBL3143238;DTXSID201175985;N-Benzyl-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine;2'-Deoxy-2'-[(3-methoxybenzoyl)amino]-N-(phenylmethyl)adenosine;218924-74-4

Suppliers and Price of N-Benzyl-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-Benzyl-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:490.19646795
Heavy Atom Count:36
Complexity:727

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C(=O)NC2C(C(OC2N3C=NC4=C(N=CN=C43)NCC5=CC=CC=C5)CO)O
Isomeric SMILES:COC1=CC=CC(=C1)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)NCC5=CC=CC=C5)CO)O

Technology Process of N-Benzyl-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine

There total 4 articles about N-Benzyl-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 218924-64-2
N⁶-benzyl-2'-deoxy-2'-(3-methoxybenzamido)-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)adenosine

: 218924-74-4
N⁶-benzyl-2'-deoxy-2'-(3-methoxybenzamido)adenosine

Guidance literature:: With ammonium fluoride; In methanol;
DOI:10.1021/jm9802620

Reference yield:

: 1711-05-3
m-anisoyl chloride

: 218924-74-4
N⁶-benzyl-2'-deoxy-2'-(3-methoxybenzamido)adenosine

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / pyridine / CH₂Cl₂ / 3 h / Heating

2: 2.) i-PrNH₂ / 1.) DMF, 45 deg C, 14 h, 2.) MeOH, reflux, 24 h

3: NH₄F / methanol

With pyridine; ammonium fluoride; isopropylamine; In methanol; dichloromethane;
DOI:10.1021/jm9802620

Reference yield:

: 586-38-9
3-Methoxybenzoic acid

: 218924-74-4
N⁶-benzyl-2'-deoxy-2'-(3-methoxybenzamido)adenosine

Guidance literature:: Multi-step reaction with 4 steps

1: PCl₅ / CH₂Cl₂ / 5 h / Ambient temperature

2: 77 percent / pyridine / CH₂Cl₂ / 3 h / Heating

3: 2.) i-PrNH₂ / 1.) DMF, 45 deg C, 14 h, 2.) MeOH, reflux, 24 h

4: NH₄F / methanol

With pyridine; ammonium fluoride; phosphorus pentachloride; isopropylamine; In methanol; dichloromethane;
DOI:10.1021/jm9802620