(-)-6-hydroxythionuphlutine

Base Information

• Chemical Name: (-)-6-hydroxythionuphlutine
• CAS No.: 183072-79-9
• Molecular Formula: C₃₀H₄₂N₂O₃S
• Molecular Weight: 510.741
• Mol file: 183072-79-9.mol

Synonyms:

Chemical Property of (-)-6-hydroxythionuphlutine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-6-hydroxythionuphlutine

There total 1 articles about (-)-6-hydroxythionuphlutine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

C31H44N2O4S → thionuphlutine B (30343-74-9) + (-)-6-hydroxythionuphlutine (183072-79-9)

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at -89 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/jacs.7b07685

Reference yield:

(-)-6-hydroxythionuphlutine (183072-79-9) → thionuphlutine B (30343-74-9)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 0.5h; Ambient temperature;

DOI:10.3987/COM-97-7878

Reference yield:

(-)-6-hydroxythionuphlutine (183072-79-9) → thiobinupharidine (30343-72-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.2 mg / CHCl₃ / 24 h / Heating

2: 19.4 mg / NaBH₄ / methanol / 0.5 h / Ambient temperature

With sodium tetrahydroborate; In methanol; chloroform;

DOI:10.3987/COM-97-7878

Downstream raw materials:

thionuphlutine B

thiobinupharidine