C₆₅H₉₉N₅O₁₂

Base Information

• Chemical Name: C₆₅H₉₉N₅O₁₂
• CAS No.: 1346119-13-8
• Molecular Formula: C₆₅H₉₉N₅O₁₂
• Molecular Weight: 1142.53
• Mol file: 1346119-13-8.mol

Synonyms:

Chemical Property of C₆₅H₉₉N₅O₁₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₅H₉₉N₅O₁₂

There total 4 articles about C₆₅H₉₉N₅O₁₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) → C65H99N5O12 (1346119-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / 5 h / Reflux

2: triethylamine; diethyl dicarbonate / tetrahydrofuran / 24 h / 0 - 20 °C

With triethylamine; diethyl dicarbonate; In tetrahydrofuran; toluene;

DOI:10.1021/bc2002874

Reference yield:

N,N'-di-[(phenylmethoxy)carbonyl]-L-lysine (405-39-0) → C65H99N5O12 (1346119-13-8)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine; diethyl dicarbonate / chloroform / 24.5 h / 0 - 20 °C

2: methanol; sodium hydroxide / 1 h / 20 °C

3: triethylamine; diethyl dicarbonate / tetrahydrofuran / 24 h / 0 - 20 °C

With methanol; triethylamine; diethyl dicarbonate; sodium hydroxide; In tetrahydrofuran; chloroform;

DOI:10.1021/bc2002874

Reference yield:

Nα,Nε-Bis(benzyloxycarbonyl)-L-lysyl-Nε-(benzyloxycarbonyl)-L-lysine Methyl Ester (13523-84-7,97485-07-9) → C65H99N5O12 (1346119-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; sodium hydroxide / 1 h / 20 °C

2: triethylamine; diethyl dicarbonate / tetrahydrofuran / 24 h / 0 - 20 °C

With methanol; triethylamine; diethyl dicarbonate; sodium hydroxide; In tetrahydrofuran;

DOI:10.1021/bc2002874

upstream raw materials:

L-glutamic acid

N,N'-di-[(phenylmethoxy)carbonyl]-L-lysine

N^α,N^ε-Bis(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Methyl Ester

methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride