(S)-3-ethoxy-3-oxo-1-phenylpropyl decanoate

Base Information

Chemical Name:(S)-3-ethoxy-3-oxo-1-phenylpropyl decanoate
CAS No.:1351766-80-7
Molecular Formula:C₂₁H₃₂O₄
Molecular Weight:348.483
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-3-ethoxy-3-oxo-1-phenylpropyl decanoate

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Technology Process of (S)-3-ethoxy-3-oxo-1-phenylpropyl decanoate

There total 2 articles about (S)-3-ethoxy-3-oxo-1-phenylpropyl decanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1351766-79-4
3-ethoxy-3-oxo-1-phenylpropyl decanoate

: 1351766-80-7
(S)-3-ethoxy-3-oxo-1-phenylpropyl decanoate

: 1351766-64-7
(R)-3-ethoxy-3-oxo-1-phenylpropyl decanoate

: 72656-47-4
ethyl (R)-3-hydroxy-3-phenylpropanoate

Guidance literature:: With Candida rugose type VII lipase; water; In di-isopropyl ether; at 20 ℃; for 15h; optical yield given as %ee; enantioselective reaction; Enzymatic reaction;
DOI:10.1016/j.tetasy.2011.09.005

Reference yield:

: 5764-85-2
Ethyl 3-hydroxy-3-phenylpropanoate

: 112-13-0
n-decanoyl chloride

: 1351766-80-7
(S)-3-ethoxy-3-oxo-1-phenylpropyl decanoate

: 1351766-64-7
(R)-3-ethoxy-3-oxo-1-phenylpropyl decanoate

: 72656-47-4
ethyl (R)-3-hydroxy-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; dmap / dichloromethane / 20 °C

2: Candida rugose type VII lipase; water / di-isopropyl ether / 15 h / 20 °C / Enzymatic reaction

With pyridine; dmap; Candida rugose type VII lipase; water; In dichloromethane; di-isopropyl ether;
DOI:10.1016/j.tetasy.2011.09.005