(+)-Ethyl (R)-3-hydroxy-3-phenylpropionate

Base Information

Chemical Name:(+)-Ethyl (R)-3-hydroxy-3-phenylpropionate
CAS No.:72656-47-4
Molecular Formula:C11H14O3
Molecular Weight:194.23
Hs Code.:2918199090
UNII:X4KRB2P77S
DSSTox Substance ID:DTXSID00357480
Nikkaji Number:J61.920E
Wikidata:Q27293551
Mol file:72656-47-4.mol

Synonyms:72656-47-4;(+)-Ethyl (R)-3-hydroxy-3-phenylpropionate;ethyl (3R)-3-hydroxy-3-phenylpropanoate;(R)-Ethyl 3-hydroxy-3-phenylpropanoate;X4KRB2P77S;Ethyl (R)-3-hydroxy-3-phenylpropionate;Ethyl 3-phenylhydracrylate, (+)-;Ethyl 3-phenylhydracrylate, (R)-;ethyl (r)-3-hydroxy-3-phenylpropanoate;(3R)-3-Hydroxy-3-phenylpropanoic acid ethyl ester;Benzenepropanoic acid, .beta.-hydroxy-, ethyl ester, (.beta.R)-;UNII-X4KRB2P77S;(R)-ethyl 3-phenylhydracrylate;SCHEMBL10391474;DTXSID00357480;AKOS017343342;(R)-Ethyl3-hydroxy-3-phenylpropanoate;(+)ethyl (R)-3-hydroxy-3-phenylpropanoate;CS-0225974;Ethyl(R)-(+)-3-hydroxy-3-phenylpropionate;EN300-125372;Q27293551;Benzenepropanoic acid, beta-hydroxy-, ethyl ester, (betaR)-;(+)-Ethyl (R)-3-hydroxy-3-phenylpropionate, >=99.0% (sum of enantiomers, GC)

Suppliers and Price of (+)-Ethyl (R)-3-hydroxy-3-phenylpropionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(+)-Ethyl (R)-3-hydroxy-3-phenylpropionate ≥99.0% (sum of enantiomers, GC)
250mg
$ 81.10

American Custom Chemicals Corporation
(+)-ETHYL (R)-3-HYDROXY-3-PHENYLPROPIONATE 95.00%
1G
$ 286.65

Total 11 raw suppliers

Chemical Property of (+)-Ethyl (R)-3-hydroxy-3-phenylpropionate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:n20/D 1.510
Boiling Point:315.296 °C at 760 mmHg
Flash Point:132.598 °C
PSA：46.53000
Density:1.119 g/cm³
LogP:1.67320
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:194.094294304
Heavy Atom Count:14
Complexity:173

Purity/Quality:

99% ^*data from raw suppliers

(+)-Ethyl (R)-3-hydroxy-3-phenylpropionate ≥99.0% (sum of enantiomers, GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 23-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(C1=CC=CC=C1)O
Isomeric SMILES:CCOC(=O)C[C@H](C1=CC=CC=C1)O

Technology Process of (+)-Ethyl (R)-3-hydroxy-3-phenylpropionate

There total 68 articles about (+)-Ethyl (R)-3-hydroxy-3-phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 72656-47-4
ethyl (R)-3-hydroxy-3-phenylpropanoate

Guidance literature:: With (S)-1-(PPh₂)-2-[CH(OMe)(C₆H₄-o-PPh₂)]-ferrocene; hydrogen; [Ru(cod)(C₄H₇)2]; hydrogen bromide; In ethanol; at 50 ℃; under 37503 Torr;
DOI:10.1002/anie.200290024

Reference yield: 100.0%

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 72656-47-4
ethyl (R)-3-hydroxy-3-phenylpropanoate

: 33401-74-0
ethyl (3R)-3-hydroxy-3-phenylpropionate

Guidance literature:: With hydrogen; C₅₀H₄₄Cl₂N₂O₈P₄Ru^(4-)*Zr⁽⁴⁺⁾; In methanol; at 20 ℃; for 20h; under 72402.6 Torr; Product distribution / selectivity;

Reference yield: 60.0%

: 100-52-7
benzaldehyde

: 105-36-2
ethyl bromoacetate

: 72656-47-4
ethyl (R)-3-hydroxy-3-phenylpropanoate

: 33401-74-0
ethyl (3R)-3-hydroxy-3-phenylpropionate

Guidance literature:: With N-((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)furan-2-carboxamide; diethylzinc; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 1h; Concentration; enantioselective reaction;
DOI:10.1007/s12039-013-0533-4