Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[5-(1,3-dihydro -1,3-dioxo-2H-isoindol-2-yl)pentyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

Base Information

Chemical Name:Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[5-(1,3-dihydro -1,3-dioxo-2H-isoindol-2-yl)pentyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
CAS No.:139212-99-0
Molecular Formula:C₆₀H₆₅N₈O₁₀P
Molecular Weight:1089.2
Hs Code.:

Adenosine,
N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[5-(1,3-dihydro
-1,3-dioxo-2H-isoindol-2-yl)pentyl]-, 3'-[2-cyanoethyl
bis(1-methylethyl)phosphoramidite]

Synonyms:

Suppliers and Price of Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[5-(1,3-dihydro -1,3-dioxo-2H-isoindol-2-yl)pentyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[5-(1,3-dihydro -1,3-dioxo-2H-isoindol-2-yl)pentyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[5-(1,3-dihydro -1,3-dioxo-2H-isoindol-2-yl)pentyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

There total 5 articles about Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[5-(1,3-dihydro -1,3-dioxo-2H-isoindol-2-yl)pentyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-88-4
benzoyl chloride

: 139212-99-0
Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-[5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-pentyloxy]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Me₃SiCl, NH₄OH

2: pyridine

3: DIEA / CH₂Cl₂

With pyridine; ammonium hydroxide; chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1016/0040-4039(91)80468-L

Reference yield:

: 136834-17-8
2-{5-[(2R,3R,4R,5R)-2-(6-Amino-purin-9-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yloxy]-pentyl}-isoindole-1,3-dione

: 139212-99-0
Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-[5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-pentyloxy]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Me₃SiCl, NH₄OH

2: pyridine

3: DIEA / CH₂Cl₂

With pyridine; ammonium hydroxide; chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1016/0040-4039(91)80468-L

Reference yield:

: 139212-97-8
N-(9-{(2R,3R,4R,5R)-3-[5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-pentyloxy]-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

: 139212-99-0
Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-[5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-pentyloxy]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine

2: DIEA / CH₂Cl₂

With pyridine; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1016/0040-4039(91)80468-L