C₁₉H₃₁N₃O₄

Base Information

• Chemical Name: C₁₉H₃₁N₃O₄
• CAS No.: 1374393-25-5
• Molecular Formula: C₁₉H₃₁N₃O₄
• Molecular Weight: 365.473
• Mol file: 1374393-25-5.mol

Synonyms:

Chemical Property of C₁₉H₃₁N₃O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₃₁N₃O₄

There total 7 articles about C₁₉H₃₁N₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(3-(benzyloxycarbonylamino)propyloxy)-4-(tert-butoxycarbonylamino)-N-isobutylbenzamide (1374393-24-4) → C19H31N3O4 (1374393-25-5)

Guidance literature:

With palladium on activated charcoal; ammonium formate; In ethanol; at 80 ℃; for 3h;

DOI:10.1002/chem.201100502

Reference yield:

4-[(tert-butoxycarbonyl)amino]-2-hydroxybenzoic acid (184033-42-9) → C19H31N3O4 (1374393-25-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 1-hydroxybenzotriazol-hydrate; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / 1.5 h / 0 °C

1.2: 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 72 h / 20 °C

3.1: water; acetic acid; zinc / 5 h / 20 °C

4.1: dmap; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 20 °C

5.1: palladium on activated charcoal; ammonium formate / ethanol / 3 h / 80 °C

With dmap; palladium on activated charcoal; water; ammonium formate; potassium carbonate; acetic acid; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dicyclohexyl-carbodiimide; zinc; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.201100502

Reference yield:

2,2,2-trichloroethyl-2-(3-(benzyloxycarbonylamino)propyloxy)-4-(tert-butoxycarbonylamino)benzoate (1374393-22-2) → C19H31N3O4 (1374393-25-5)

Guidance literature:

Multi-step reaction with 3 steps

1: water; acetic acid; zinc / 5 h / 20 °C

2: dmap; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 20 °C

3: palladium on activated charcoal; ammonium formate / ethanol / 3 h / 80 °C

With dmap; palladium on activated charcoal; water; ammonium formate; acetic acid; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; zinc; In ethanol; dichloromethane;

DOI:10.1002/chem.201100502

upstream raw materials:

4-[(tert-butoxycarbonyl)amino]-2-hydroxybenzoic acid

2,2,2-trichloroethyl-4-(tert-butoxycarbonylamino)-2-hydroxybenzoate

2,2,2-trichloroethyl-2-(3-(benzyloxycarbonylamino)propyloxy)-4-(tert-butoxycarbonylamino)benzoate

2-(3-(benzyloxycarbonylamino)propyloxy)-4-(tert-butoxycarbonylamino)benzoic acid

Downstream raw materials:

C₅₆H₅₉N₉O₇

C₅₁H₅₁N₉O₅