C₃₀H₃₁N₅O₅

Base Information

• Chemical Name: C₃₀H₃₁N₅O₅
• CAS No.: 431052-74-3
• Molecular Formula: C₃₀H₃₁N₅O₅
• Molecular Weight: 541.607
• Mol file: 431052-74-3.mol

Synonyms:

Chemical Property of C₃₀H₃₁N₅O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₃₁N₅O₅

There total 15 articles about C₃₀H₃₁N₅O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine-2-carbaldehyde (1121-60-4) → C30H31N5O5 (431052-74-3)

Guidance literature:

Multi-step reaction with 10 steps

1: N,N',N'-trimethylenediamine; n-butyllithium / tetrahydrofuran; hexane; cyclohexane

2: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / tert-butyl alcohol; acetonitrile; water

3: caesium carbonate / N,N-dimethyl-formamide

4: 3-chloro-benzenecarboperoxoic acid / dichloromethane

5: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

6: trifluoroacetic anhydride / N,N-dimethyl-formamide

7: sodium hydroxide; water / tetrahydrofuran

8: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide

9: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran

10: trifluoroacetic acid / dichloromethane

With dmap; bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; n-butyllithium; 1-hydroxy-7-aza-benzotriazole; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; di-isopropyl azodicarboxylate; water; caesium carbonate; N,N',N'-trimethylenediamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; trifluoroacetic acid; trifluoroacetic anhydride; copper(II) oxide; sodium hydroxide; In tetrahydrofuran; hexane; dichloromethane; cyclohexane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol; 9: |Mitsunobu Displacement;

DOI:10.1016/j.bmcl.2013.06.028

Reference yield:

3-(tributylstannyl)picolinaldehyde (431052-64-1) → C30H31N5O5 (431052-74-3)

Guidance literature:

Multi-step reaction with 9 steps

1: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / tert-butyl alcohol; acetonitrile; water

2: caesium carbonate / N,N-dimethyl-formamide

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane

4: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

5: trifluoroacetic anhydride / N,N-dimethyl-formamide

6: sodium hydroxide; water / tetrahydrofuran

7: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide

8: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran

9: trifluoroacetic acid / dichloromethane

With dmap; bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; 1-hydroxy-7-aza-benzotriazole; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; di-isopropyl azodicarboxylate; water; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; trifluoroacetic acid; trifluoroacetic anhydride; copper(II) oxide; sodium hydroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol; 8: |Mitsunobu Displacement;

DOI:10.1016/j.bmcl.2013.06.028

Reference yield:

C19H33NO3Sn (431052-65-2) → C30H31N5O5 (431052-74-3)

Guidance literature:

Multi-step reaction with 6 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(II) oxide / N,N-dimethyl-formamide / 110 °C

2: trifluoroacetic anhydride / N,N-dimethyl-formamide

3: sodium hydroxide; water / tetrahydrofuran

4: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide

5: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran

6: trifluoroacetic acid / dichloromethane

With dmap; bis-triphenylphosphine-palladium(II) chloride; 1-hydroxy-7-aza-benzotriazole; di-isopropyl azodicarboxylate; water; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triphenylphosphine; trifluoroacetic acid; trifluoroacetic anhydride; copper(II) oxide; sodium hydroxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 5: |Mitsunobu Displacement;

DOI:10.1016/j.bmcl.2013.06.028

upstream raw materials:

pyridine-2-carbaldehyde

3-(tributylstannyl)picolinaldehyde

C₁₉H₃₃NO₃Sn

C₂₃H₂₈N₂O₆