C₂₇H₃₂N₁₀O₄

Base Information

• Chemical Name: C₂₇H₃₂N₁₀O₄
• CAS No.: 1359164-20-7
• Molecular Formula: C₂₇H₃₂N₁₀O₄
• Molecular Weight: 560.616
• Mol file: 1359164-20-7.mol

Synonyms:

Chemical Property of C₂₇H₃₂N₁₀O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₂N₁₀O₄

There total 3 articles about C₂₇H₃₂N₁₀O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 4-benzamido-1-methylimidazole-2-carboxylate (1359164-22-9) → C27H32N10O4 (1359164-20-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide / methanol; water / 0.75 h / Reflux

1.2: pH 3 - 4

2.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C

2.2: 72 h / 20 °C

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2011.12.010

Reference yield:

ethyl 1-methyl-4-nitroimidazole-2-carboxylate (109012-23-9) → C27H32N10O4 (1359164-20-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 5%-palladium/activated carbon; hydrogen / ethanol / 12 h / 20 °C

2.1: triethylamine / dichloromethane / 12 h / 0 - 20 °C

3.1: sodium hydroxide / methanol; water / 0.75 h / Reflux

3.2: pH 3 - 4

4.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C

4.2: 72 h / 20 °C

With 5%-palladium/activated carbon; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; triethylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2011.12.010

Reference yield:

ethyl 4-amino-1-methylimidazole-2-carboxylate (128293-62-9) → C27H32N10O4 (1359164-20-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 12 h / 0 - 20 °C

2.1: sodium hydroxide / methanol; water / 0.75 h / Reflux

2.2: pH 3 - 4

3.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C

3.2: 72 h / 20 °C

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2011.12.010

upstream raw materials:

ethyl 4-benzamido-1-methylimidazole-2-carboxylate

ethyl 4-amino-1-methylimidazole-2-carboxylate

ethyl 1-methyl-4-nitroimidazole-2-carboxylate