C₂₇H₃₄N₂O₄

Base Information

• Chemical Name: C₂₇H₃₄N₂O₄
• CAS No.: 1247088-52-3
• Molecular Formula: C₂₇H₃₄N₂O₄
• Molecular Weight: 450.578
• Mol file: 1247088-52-3.mol

Synonyms:

Chemical Property of C₂₇H₃₄N₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₄N₂O₄

There total 5 articles about C₂₇H₃₄N₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl {2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl}carbamate (1247090-07-8) → C27H34N2O4 (1247088-52-3)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate / tetrahydrofuran; water

2: palladium on activated charcoal; hydrogen / ethanol

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium on activated charcoal; hydrogen; palladium diacetate; In tetrahydrofuran; ethanol; water; 1: Suzuki coupling;

DOI:10.1016/j.bmcl.2012.01.044

Reference yield:

rac-tert-butyl 3-(4-hydroxy-2-methylphenyl)-4-oxo-1-piperidinecarboxylate (1247091-09-3) → C27H34N2O4 (1247088-52-3)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / dichloromethane

2: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate / tetrahydrofuran; water

3: palladium on activated charcoal; hydrogen / ethanol

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; pyridine; potassium phosphate; palladium on activated charcoal; hydrogen; palladium diacetate; In tetrahydrofuran; ethanol; dichloromethane; water; 2: Suzuki coupling;

DOI:10.1016/j.bmcl.2012.01.044

Reference yield:

C18H22F3NO6S (1247088-47-6) → C27H34N2O4 (1247088-52-3)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate / tetrahydrofuran; water

2: palladium on activated charcoal; hydrogen / ethanol

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium on activated charcoal; hydrogen; palladium diacetate; In tetrahydrofuran; ethanol; water; 1: Suzuki coupling;

DOI:10.1016/j.bmcl.2012.01.044

upstream raw materials:

benzyl {2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl}carbamate

rac-tert-butyl 3-(4-hydroxy-2-methylphenyl)-4-oxo-1-piperidinecarboxylate

C₁₈H₂₂F₃NO₆S

C₃₃H₃₈N₂O₅

Downstream raw materials:

C₃₄H₄₄N₂O₄

C₃₉H₅₂N₂O₆

C₃₃H₄₀F₂N₂O₄

C₃₈H₄₈F₂N₂O₆