C₂₄H₁₉N₃O

Base Information

• Chemical Name: C₂₄H₁₉N₃O
• CAS No.: 1610051-23-4
• Molecular Formula: C₂₄H₁₉N₃O
• Molecular Weight: 365.434
• Mol file: 1610051-23-4.mol

Synonyms:

Chemical Property of C₂₄H₁₉N₃O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₁₉N₃O

There total 4 articles about C₂₄H₁₉N₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H17N3O (1610051-70-1) + methyl iodide (74-88-4) → C24H19N3O (1610051-23-4)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at 50 ℃; for 2h;

DOI:10.1016/j.bmcl.2014.04.051 DOI:10.1016/j.bmcl.2014.04.051

Reference yield:

C17H12BrN3O (1610051-91-6) → C24H19N3O (1610051-23-4)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium phosphate / 1,4-dioxane; water / 0.67 h / 130 °C / Microwave irradiation

2: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / 50 °C

With potassium phosphate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; water; 1: |Suzuki Coupling;

DOI:10.1016/j.bmcl.2014.04.051

Reference yield:

2-amino-4-bromobenzoic acid (20776-50-5) → C24H19N3O (1610051-23-4)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium nitrite; hydrogenchloride; tin(ll) chloride / 2 h / -5 - 20 °C

2: acetic acid / 0.08 h / 150 °C / Microwave irradiation

3: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium phosphate / 1,4-dioxane; water / 0.67 h / 130 °C / Microwave irradiation

4: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / 50 °C

With hydrogenchloride; potassium phosphate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; acetic acid; tin(ll) chloride; lithium hexamethyldisilazane; sodium nitrite; In tetrahydrofuran; 1,4-dioxane; water; 3: |Suzuki Coupling;

DOI:10.1016/j.bmcl.2014.04.051

upstream raw materials:

C₂₃H₁₇N₃O

methyl iodide

C₁₇H₁₂BrN₃O

2-amino-4-bromobenzoic acid