IpratropiuM BroMide IMpurity E

Base Information

Chemical Name:IpratropiuM BroMide IMpurity E
CAS No.:183626-76-8
Molecular Formula:C₁₉H₂₇NO₃
Molecular Weight:317.428
Hs Code.:
Mol file:183626-76-8.mol

Synonyms:

Suppliers and Price of IpratropiuM BroMide IMpurity E

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of IpratropiuM BroMide IMpurity E

Chemical Property:

Boiling Point:448.8±45.0 °C(Predicted)
PKA:14.12±0.10(Predicted)
Density:1.15±0.1 g/cm3(Predicted)

Purity/Quality:: > 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (S)-(1R,3r,5S)-8-Isopropyl-8-azabicyclo[3.2.1]octan-3-yl 3-Hydroxy-2-phenylpropanoate is a compound that can be synthesized from Atropine (A794630), a nerve agent that occurs naturally in plants of the nightshade family.

Technology Process of IpratropiuM BroMide IMpurity E

There total 9 articles about IpratropiuM BroMide IMpurity E which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.6%

: α-formylphenylacetic acid N-isopropylnortropine ester

: 22235-81-0,183626-76-8
(1R,3R,5S)-3'-hydroxy-2'-phenylpropionic acid 8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl ester

Guidance literature:: With potassium borohydride; In chloroform; water; at 0 - 10 ℃; for 4h; Reagent/catalyst; Temperature; Solvent;

Reference yield: 62.0%

: 67-64-1
acetone

: 16839-98-8
Noratropine

: 22235-81-0,183626-76-8
(1R,3R,5S)-3'-hydroxy-2'-phenylpropionic acid 8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl ester

Guidance literature:: With sodium cyanoborohydride; acetic acid; In methanol; at 20 ℃; for 4.5h; pH=7;
DOI:10.1071/CH05303

Reference yield:

: 3423-25-4
endo-8-(1-methylethyl)-8-azabicyclo<3.2.1>octan-3-ol

: 22235-81-0,183626-76-8
(1R,3R,5S)-3'-hydroxy-2'-phenylpropionic acid 8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 4 h / 85 °C

2: 0.89 g / hydrochloric acid / CHCl₃ / 18 h

With hydrogenchloride; In chloroform;
DOI:10.1080/00397910601039119