Technology Process of C43H47N5O
There total 6 articles about C43H47N5O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium tert-butylate / tetrahydrofuran / 1 h / -78 - 0 °C / Inert atmosphere
1.2: 69 h / 0 - 20 °C
2.1: copper(II) sulfate; sodium L-ascorbate / dichloromethane; water; tert-butyl alcohol / 12 h / 20 °C
3.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / tetrahydrofuran; water / 20 h / 69 °C
4.1: isopropylmagnesium chloride / tetrahydrofuran / 2 h / -20 - 0 °C / Inert atmosphere
5.1: tetrahydrofuran / -20 - 20 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; potassium tert-butylate; isopropylmagnesium chloride; sodium carbonate; copper(II) sulfate; sodium L-ascorbate;
In
tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;
DOI:10.1002/cmdc.201100316
- Guidance literature:
-
Multi-step reaction with 4 steps
1: copper(II) sulfate; sodium L-ascorbate / dichloromethane; water; tert-butyl alcohol / 12 h / 20 °C
2: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / tetrahydrofuran; water / 20 h / 69 °C
3: isopropylmagnesium chloride / tetrahydrofuran / 2 h / -20 - 0 °C / Inert atmosphere
4: tetrahydrofuran / -20 - 20 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; isopropylmagnesium chloride; sodium carbonate; copper(II) sulfate; sodium L-ascorbate;
In
tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;
DOI:10.1002/cmdc.201100316
- Guidance literature:
-
Multi-step reaction with 3 steps
1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / tetrahydrofuran; water / 20 h / 69 °C
2: isopropylmagnesium chloride / tetrahydrofuran / 2 h / -20 - 0 °C / Inert atmosphere
3: tetrahydrofuran / -20 - 20 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; isopropylmagnesium chloride; sodium carbonate;
In
tetrahydrofuran; water;
DOI:10.1002/cmdc.201100316