3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-[1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl]-, methyl ester, trans-

Base Information

• Chemical Name: 3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-[1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl]-, methyl ester, trans-
• CAS No.: 139285-05-5
• Molecular Formula: C20H24N2O4S
• Molecular Weight: 388.488
• Mol file: 139285-05-5.mol

Synonyms:

Chemical Property of 3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-[1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl]-, methyl ester, trans-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-[1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl]-, methyl ester, trans-

There total 3 articles about 3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-[1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl]-, methyl ester, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

methyl (E)-3-<1-(p-toluenesulfonyl)-1H-imidazol-4(5)-yl>propenoate (139284-99-4) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → methyl trans-4,5-dimethyl-2-<1-(p-toluenesulfonyl)-1H-imidazol-4(5)-yl>cyclohex-4-ene-1-carboxylate (139285-05-5)

Guidance literature:

With hydroquinone; In benzene; at 140 - 170 ℃; for 144h;

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → methyl trans-4,5-dimethyl-2-<1-(p-toluenesulfonyl)-1H-imidazol-4(5)-yl>cyclohex-4-ene-1-carboxylate (139285-05-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / Na₂CO₃ / ethyl acetate; H₂O / Ambient temperature

2: 58 percent / hydroquinone / benzene / 144 h / 140 - 170 °C

With sodium carbonate; hydroquinone; In water; ethyl acetate; benzene;

Reference yield:

(E)-methyl 3-(1H-imidazol-4-yl)acrylate (70346-51-9) → methyl trans-4,5-dimethyl-2-<1-(p-toluenesulfonyl)-1H-imidazol-4(5)-yl>cyclohex-4-ene-1-carboxylate (139285-05-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / Na₂CO₃ / ethyl acetate; H₂O / Ambient temperature

2: 58 percent / hydroquinone / benzene / 144 h / 140 - 170 °C

With sodium carbonate; hydroquinone; In water; ethyl acetate; benzene;

upstream raw materials:

methyl (E)-3-<1-(p-toluenesulfonyl)-1H-imidazol-4(5)-yl>propenoate

2,3-dimethyl-buta-1,3-diene

p-toluenesulfonyl chloride

(E)-methyl 3-(1H-imidazol-4-yl)acrylate