2-(2-METHYL-1,3-BENZOXAZOL-5-YL)ACETIC ACID

Base Information

• Chemical Name: 2-(2-METHYL-1,3-BENZOXAZOL-5-YL)ACETIC ACID
• CAS No.: 38196-01-9
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.186
• Hs Code.: 2934999090
• Mol file: 38196-01-9.mol

Synonyms:

Chemical Property of 2-(2-METHYL-1,3-BENZOXAZOL-5-YL)ACETIC ACID

Chemical Property:

• Boiling Point: 358.3±17.0 °C(Predicted)
• PKA: 3.92±0.30(Predicted)
• Density: 1.334±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

2-(2-METHYL-1,3-BENZOXAZOL-5-YL)ACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-METHYL-1,3-BENZOXAZOL-5-YL)ACETIC ACID

There total 2 articles about 2-(2-METHYL-1,3-BENZOXAZOL-5-YL)ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-3-nitrophenylacetic acid (10463-20-4) → 2-(2-methylbenzo[d]oxazol-5-yl)acetic acid (38196-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂, aq. NaHCO₃ / Pd-C

2: methanol

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In methanol;

Reference yield:

ethyl acetimidate hydrochloride (2208-07-3) + 4-hydroxy-3-amino-phenylacetic acid (38196-08-6) → 2-(2-methylbenzo[d]oxazol-5-yl)acetic acid (38196-01-9)

Guidance literature:

In methanol;

upstream raw materials:

ethyl acetimidate hydrochloride

4-hydroxy-3-amino-phenylacetic acid

4-hydroxy-3-nitrophenylacetic acid