(1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide

Base Information

Chemical Name:(1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide
CAS No.:1312766-79-2
Molecular Formula:C₉H₉F₃N₂O
Molecular Weight:218.178
Hs Code.:

Synonyms:

Suppliers and Price of (1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of (1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

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Technology Process of (1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide

There total 1 articles about (1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.9%

: 2338-75-2
4-(Trifluoromethyl)phenylacetonitrile

: 1312766-79-2,176860-56-3
(1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide

Guidance literature:: With hydroxylamine hydrochloride; sodium hydrogencarbonate; In methanol; for 4h; Heating / reflux;

Reference yield: 89.0%

: 1312766-79-2,176860-56-3
(1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide

: 36239-09-5
ethyl chlorocarbonylacetate

: 1028344-71-9
C₁₄H₁₃F₃N₂O₃

Guidance literature:: (1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide; With sodium hydride; In toluene; mineral oil; at 20 ℃; for 1h; Inert atmosphere;

ethyl chlorocarbonylacetate; In toluene; mineral oil; Inert atmosphere; Reflux;
DOI:10.1021/jm701613h

Reference yield: 4.4%

: 3-(7-bromo-5-oxo-9-pentyl-6,9-dihydro-5H-[1,2,4]triazolo[4,3-a]purin-3-yl)propanoic acid

: 1312766-79-2,176860-56-3
(1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide

: 7-bromo-9-pentyl-3-(2-3-[4-(trifluoromethyl)benzyl]-1,2,4-oxadiazol-5-ylethyl)-6,9-dihydro-5H-pyrrolo[3,2-d][1,2,4]triazolo[4,3-a]pyrimidin-5-one

Guidance literature:: 3-(7-bromo-5-oxo-9-pentyl-6,9-dihydro-5H-[1,2,4]triazolo[4,3-a]purin-3-yl)propanoic acid; With 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

(1Z)-N'-hydroxy-2-[4-(trifluoromethyl)phenyl]ethanimidamide; In N,N-dimethyl-formamide; at 90 - 110 ℃; for 24h;