3-Furancarboxylic acid, 2-[(phenylthio)methyl]-

Base Information

• Chemical Name: 3-Furancarboxylic acid, 2-[(phenylthio)methyl]-
• CAS No.: 139308-36-4
• Molecular Formula: C12H10O3S
• Molecular Weight: 234.276
• Mol file: 139308-36-4.mol

Synonyms:

Chemical Property of 3-Furancarboxylic acid, 2-[(phenylthio)methyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Furancarboxylic acid, 2-[(phenylthio)methyl]-

There total 4 articles about 3-Furancarboxylic acid, 2-[(phenylthio)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-Phenylsulfanylmethyl-furan-3-carboxylic acid methyl ester (139308-33-1) → 2-(phenylthiomethyl)-3-furancarboxylic acid (139308-36-4)

Guidance literature:

With potassium hydroxide; In methanol; water; for 4h; Heating;

Reference yield:

2-chloromethylfuran-3-carboxylate (53020-07-8) → 2-(phenylthiomethyl)-3-furancarboxylic acid (139308-36-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaOMe, / 1.) DMSO, 2.) DMSO, RT, 4 h

2: 87 percent / KOH / methanol; H₂O / 4 h / Heating

With potassium hydroxide; sodium methylate; In methanol; water;

Reference yield:

thiophenol (108-98-5) → 2-(phenylthiomethyl)-3-furancarboxylic acid (139308-36-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaOMe, / 1.) DMSO, 2.) DMSO, RT, 4 h

2: 87 percent / KOH / methanol; H₂O / 4 h / Heating

With potassium hydroxide; sodium methylate; In methanol; water;

upstream raw materials:

2-Phenylsulfanylmethyl-furan-3-carboxylic acid methyl ester

2-chloromethylfuran-3-carboxylate

thiophenol

Downstream raw materials:

2-Phenylsulfanylmethyl-furan-3-carbonyl azide

Refernces

• 1、 -. "Antidiabetic furancarboxylic and thiphenecarboxylic acids". . . Retrieved 2008/06/13.