Methyl 2-(chloromethyl)-3-furoate

Base Information

• Chemical Name: Methyl 2-(chloromethyl)-3-furoate
• CAS No.: 53020-07-8
• Molecular Formula: C7H7ClO3
• Molecular Weight: 174.584
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID90365933
• Wikidata: Q82150977
• Mol file: 53020-07-8.mol

Synonyms:methyl 2-(chloromethyl)-3-furoate;53020-07-8;methyl 2-(chloromethyl)furan-3-carboxylate;METHYL2-(CHLOROMETHYL)-3-FUROATE;SCHEMBL3823759;DTXSID90365933;GAZIBZAQRRDIMQ-UHFFFAOYSA-N;MFCD04971664;AKOS001368988;AT17457;EN300-27099;2-chloromethyl-furan-3-carboxylic acid methyl ester;F1901-0078

Chemical Property of Methyl 2-(chloromethyl)-3-furoate

Chemical Property:

• Boiling Point: 257.8±30.0 °C(Predicted)
• PSA: 39.44000
• Density: 1.266±0.06 g/cm3(Predicted)
• LogP: 1.80500
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 174.0083718
• Heavy Atom Count: 11
• Complexity: 149

Purity/Quality:

methyl2-(chloromethyl)furan-3-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=C(OC=C1)CCl

Technology Process of Methyl 2-(chloromethyl)-3-furoate

There total 1 articles about Methyl 2-(chloromethyl)-3-furoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-chloromethylfuran-3-carboxylate (53020-07-8)

Guidance literature:

6, Chloracetaldehyd, Na2CO3;

Reference yield: 80.0%

salicylonitrile (611-20-1) + 2-chloromethylfuran-3-carboxylate (53020-07-8) → methyl 2-[(2-cyanophenoxy)methyl]-3-furoate

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 2h;

DOI:10.1515/hc-2017-0143

Reference yield: 78.0%

2-chloromethylfuran-3-carboxylate (53020-07-8) + 5-bromo-2-hydroxybenzonitrile (40530-18-5) → methyl 2-[(4-bromo-2-cyanophenoxy)methyl]-3-furoate

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 2h;

DOI:10.1515/hc-2017-0143

Downstream raw materials:

2-Phenylsulfanylmethyl-furan-3-carboxylic acid methyl ester

2-(phenylthiomethyl)-3-furancarboxylic acid

2-Phenylsulfanylmethyl-furan-3-carbonyl azide