6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE

Base Information

Chemical Name:6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE
CAS No.:67130-66-9
Molecular Formula:C₈H₁₀ClN₃O₃
Molecular Weight:231.639
Hs Code.:2933599090
Mol file:67130-66-9.mol

Synonyms:2,4(1H,3H)-Pyrimidinedione,6-amino-5-(chloroacetyl)-1,3-dimethyl- (9CI); 4-Amino-5-chloroacetyl-1,3-dimethyluracil;NSC 79228

Suppliers and Price of 6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Amino-5-(chloroacetyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
500mg
$ 350.00

American Custom Chemicals Corporation
6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE 95.00%
2.5G
$ 1119.71

American Custom Chemicals Corporation
6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE 95.00%
1G
$ 386.40

AK Scientific
6-Amino-5-(chloroacetyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
100mg
$ 228.00

Total 9 raw suppliers

Chemical Property of 6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE

Chemical Property:

Vapor Pressure:0.00013mmHg at 25°C
Boiling Point:334.1°C at 760 mmHg
Flash Point:155.9°C
PSA：87.09000
Density:1.438g/cm³
LogP:-0.33110

Purity/Quality:

97% ^*data from raw suppliers

6-Amino-5-(chloroacetyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE

There total 2 articles about 6-AMINO-5-(2-CHLORO-ACETYL)-1,3-DIMETHYL-1H-PYRIMIDINE-2,4-DIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 6642-31-5
6-Amino-1,3-dimethylbarbituric acid

: 79-04-9
chloroacetyl chloride

: 67130-66-9
6-Amino-5-(2-chloracetyl)-1,3-dimethyl-2,4(1H,3H)pyrimidindion

Guidance literature:: With pyridine; In 1,4-dioxane; at 20 ℃; for 6h;

Reference yield:

: 67130-66-9
6-Amino-5-(2-chloracetyl)-1,3-dimethyl-2,4(1H,3H)pyrimidindion

Guidance literature:: 1,3-Dimethyl-6-aminouracil, ClCH2COCl/ClCH2COOH, Pyridin;
DOI:10.1007/BF00472164

Reference yield:

: 67130-66-9
6-Amino-5-(2-chloracetyl)-1,3-dimethyl-2,4(1H,3H)pyrimidindion

: 1-(1,3,7-Trimethyl-2,4,5-trioxo-1,2,3,4,5,8-hexahydro-pyrido[2,3-d]pyrimidin-6-yl)-pyridiniumchlorid

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / conc. HClO₄ / 2 h / 0 °C

2: 86 percent / butan-1-ol / 0.33 h / Heating

With perchloric acid; In butan-1-ol; 1: Acetylation / 2: cyclocondensation;