1-(3-Nitrophenyl)-1H-pyrazol-3-amine

Base Information

Chemical Name:1-(3-Nitrophenyl)-1H-pyrazol-3-amine
CAS No.:127530-36-3
Molecular Formula:C₉H₈N₄O₂
Molecular Weight:204.188
Hs Code.:
DSSTox Substance ID:DTXSID301291413
Nikkaji Number:J277.073C

Synonyms:1-(3-Nitrophenyl)-1H-pyrazol-3-amine;127530-36-3;SCHEMBL11465754;DTXSID301291413;AKOS011973083;F70552

Suppliers and Price of 1-(3-Nitrophenyl)-1H-pyrazol-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-(3-Nitrophenyl)-1H-pyrazol-3-amine

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:204.06472551
Heavy Atom Count:15
Complexity:243

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)[N+](=O)[O-])N2C=CC(=N2)N

Technology Process of 1-(3-Nitrophenyl)-1H-pyrazol-3-amine

There total 3 articles about 1-(3-Nitrophenyl)-1H-pyrazol-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 131319-56-7
1-(m-nitrophenyl)-3-acetamidopyrazole

: 127530-36-3
1-(m-nitrophenyl)-3-aminopyrazole

Guidance literature:: With hydrogenchloride; In ethanol; for 3h; Heating;

Reference yield:

: 645-00-1
m-iodonitrobenzene

: 1820-80-0,916420-28-5
3-aminopyrazole

: 127530-36-3
1-(m-nitrophenyl)-3-aminopyrazole

: 16459-43-1
2-(3-nitro-phenyl)-2H-pyrazol-3-ylamine

Guidance literature:: With copper(l) iodide; caesium carbonate; In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 24h; Overall yield = 75 %; regioselective reaction;
DOI:10.1002/cctc.201500510

Reference yield:

: 585-79-5
m-nitrobromobenzene

: 127530-36-3
1-(m-nitrophenyl)-3-aminopyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: 39 percent / K₂CO₃, CuO, pyridine / Heating

2: 42 percent / conc. HCl / ethanol / 3 h / Heating

With pyridine; hydrogenchloride; potassium carbonate; copper(II) oxide; In ethanol;