PHENYL[(THIEN-2-YLCARBONYL)AMINO]ACETIC ACID

Base Information

• Chemical Name: PHENYL[(THIEN-2-YLCARBONYL)AMINO]ACETIC ACID
• CAS No.: 1008670-87-8
• Molecular Formula: C₁₃H₁₁NO₃S
• Molecular Weight: 261.301
• Mol file: 1008670-87-8.mol

Synonyms:

Chemical Property of PHENYL[(THIEN-2-YLCARBONYL)AMINO]ACETIC ACID

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2-Phenyl-2-(thiophen-2-ylformamido)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of PHENYL[(THIEN-2-YLCARBONYL)AMINO]ACETIC ACID

There total 1 articles about PHENYL[(THIEN-2-YLCARBONYL)AMINO]ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Thiophenecarbonyl chloride (5271-67-0) + phenylglycin (2835-06-5) → phenyl-(thiophene-2-carbonylamino)-acetic acid (1008670-87-8)

Guidance literature:

With sodium hydroxide; at 20 ℃;

DOI:10.1039/c9cc01450k

Reference yield: 33.0%

N-Ts a-bromo-hydrazone (57598-59-1) + phenyl-(thiophene-2-carbonylamino)-acetic acid (1008670-87-8) → N-(3-oxo-4,6-diphenyl-2-tosyl-2,3,4,5-tetrahydropyridazin-4-yl)-thiophene-2-carboxamide

Guidance literature:

With sodium carbonate; dicyclohexyl-carbodiimide; In toluene; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.joc.0c01592

upstream raw materials:

2-Thiophenecarbonyl chloride

phenylglycin

Refernces