Technology Process of 2-([1,1'-bi(cyclopropan)]-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
There total 4 articles about 2-([1,1'-bi(cyclopropan)]-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-bromo-1-cyclopropylcyclopropane;
With
tert.-butyl lithium;
In
diethyl ether; pentane;
at -78 ℃;
for 1h;
Inert atmosphere;
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;
In
diethyl ether; pentane;
at -78 - 20 ℃;
for 6h;
Inert atmosphere;
DOI:10.1002/ejoc.201000209
- Guidance literature:
-
With
iodotrifluoromethane;
In
dimethyl sulfoxide; acetonitrile;
at 20 ℃;
for 1h;
regioselective reaction;
Inert atmosphere;
Schlenk technique;
Irradiation;
DOI:10.1021/jacs.9b07960
- Guidance literature:
-
Multi-step reaction with 2 steps
1: diethyl ether / 1.08 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2: iodotrifluoromethane / acetonitrile; dimethyl sulfoxide / 1 h / 20 °C / Inert atmosphere; Schlenk technique; Irradiation
With
iodotrifluoromethane;
In
diethyl ether; dimethyl sulfoxide; acetonitrile;
DOI:10.1021/jacs.9b07960
