6a,11a-Dihydro-6,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol

Base Information

Chemical Name:6a,11a-Dihydro-6,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol
CAS No.:1674359-82-0
Molecular Formula:C₁₇H₁₆O₅
Molecular Weight:300.311
Hs Code.:
Mol file:1674359-82-0.mol

Synonyms:

Suppliers and Price of 6a,11a-Dihydro-6,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 6a,11a-Dihydro-6,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol

Chemical Property:

Purity/Quality:: 98.0% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6a,11a-Dihydro-6,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol

There total 12 articles about 6a,11a-Dihydro-6,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₂₀O₇

: 1674359-82-0
(-)-6,9-dimethoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3-ol

Guidance literature:: With potassium carbonate; In ethyl acetate; at 20 ℃; for 5h;
DOI:10.1002/anie.201408910

Reference yield:

: (2S,3R)-3-(2-hydroxy-4-methoxyphenyl)-2-(((1R,2S)-2-phenylcyclohexyl)oxy)chroman-7-ol

: 1674359-82-0
(-)-6,9-dimethoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3-ol

Guidance literature:: Multi-step reaction with 7 steps

1: sodium hydride / N,N-dimethyl-formamide / 5 h / -78 - 20 °C / Inert atmosphere

2: camphor-10-sulfonic acid; hydrogenchloride / acetonitrile; water / 16 h / Reflux

3: thionyl chloride / N,N-dimethyl-formamide; dichloromethane / 3 h / 0 - 20 °C

4: silver carbonate / dichloromethane / Molecular sieve

5: lead(II,IV) oxide / benzene / 3 h / 85 °C

6: palladium 10% on activated carbon; hydrogen / ethanol

7: potassium carbonate / ethyl acetate / 5 h / 20 °C

With hydrogenchloride; thionyl chloride; lead(II,IV) oxide; palladium 10% on activated carbon; camphor-10-sulfonic acid; hydrogen; sodium hydride; potassium carbonate; silver carbonate; In ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; benzene;
DOI:10.1002/anie.201408910

Reference yield:

: (2S,3R)-7-(benzyloxy)-3-(2-(benzyloxy)-4-methoxyphenyl)-2-(((1R,2S)-2-phenylcyclohexyl)oxy)chroman

: 1674359-82-0
(-)-6,9-dimethoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3-ol

Guidance literature:: Multi-step reaction with 6 steps

1: camphor-10-sulfonic acid; hydrogenchloride / acetonitrile; water / 16 h / Reflux

2: thionyl chloride / N,N-dimethyl-formamide; dichloromethane / 3 h / 0 - 20 °C

3: silver carbonate / dichloromethane / Molecular sieve

4: lead(II,IV) oxide / benzene / 3 h / 85 °C

5: palladium 10% on activated carbon; hydrogen / ethanol

6: potassium carbonate / ethyl acetate / 5 h / 20 °C

With hydrogenchloride; thionyl chloride; lead(II,IV) oxide; palladium 10% on activated carbon; camphor-10-sulfonic acid; hydrogen; potassium carbonate; silver carbonate; In ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; benzene;
DOI:10.1002/anie.201408910