C₇₄H₅₀N₄O₃Pd

Base Information

• Chemical Name: C₇₄H₅₀N₄O₃Pd
• CAS No.: 1403938-55-5
• Molecular Formula: C₇₄H₅₀N₄O₃Pd
• Molecular Weight: 1149.66
• Mol file: 1403938-55-5.mol

Synonyms:

Chemical Property of C₇₄H₅₀N₄O₃Pd

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₄H₅₀N₄O₃Pd

There total 6 articles about C₇₄H₅₀N₄O₃Pd which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C45H28N4O2Pd (1083057-29-7) + 2-((1-(9H-fluoren-9-ylidene)-2-methyl-2,3-dihydro-1H-cyclopenta[a]naphthalen-5-yl)oxy)ethanol (1403891-57-5) → C74H50N4O3Pd (1403938-41-9,1403938-55-5,1403938-59-9)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 20h; Darkness;

DOI:10.1021/ja306986g

Reference yield:

5-hydroxy-2-methyl-2,3-dihydro-1H-cyclopenta[a]naphthalen-1-one (1403891-53-1) → C74H50N4O3Pd (1403938-41-9,1403938-55-5,1403938-59-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 50 °C

2.1: Lawessons reagent / tetrahydrofuran / 3.5 h / 50 °C

3.1: toluene / 16 h / 50 °C

3.2: 16 h / Reflux

3.3: 3 h / 20 °C

4.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C

5.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 h / 20 °C / Darkness

With Lawessons reagent; dmap; lithium aluminium tetrahydride; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; 3.1: |Barton-Kellog Olefination / 3.2: |Barton-Kellog Olefination;

DOI:10.1021/ja306986g

Reference yield:

5-methoxy-2-methyl-2,3-dihydro-1H-cyclopenta[a]naphthalen-1-one (1025325-46-5) → C74H50N4O3Pd (1403938-41-9,1403938-55-5,1403938-59-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: pyridine hydrochloride / 2 h / 150 - 190 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 50 °C

3.1: Lawessons reagent / tetrahydrofuran / 3.5 h / 50 °C

4.1: toluene / 16 h / 50 °C

4.2: 16 h / Reflux

4.3: 3 h / 20 °C

5.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C

6.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 h / 20 °C / Darkness

With Lawessons reagent; dmap; lithium aluminium tetrahydride; pyridine hydrochloride; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; 4.1: |Barton-Kellog Olefination / 4.2: |Barton-Kellog Olefination;

DOI:10.1021/ja306986g

upstream raw materials:

C₄₅H₂₈N₄O₂Pd

2-((1-(9H-fluoren-9-ylidene)-2-methyl-2,3-dihydro-1H-cyclopenta[a]naphthalen-5-yl)oxy)ethanol

5-hydroxy-2-methyl-2,3-dihydro-1H-cyclopenta[a]naphthalen-1-one

1-Methoxynaphthalene