(S)-1-{(S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carboxylic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid

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Chemical Name:(S)-1-{(S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carboxylic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid
CAS No.:80574-74-9
Molecular Formula:C₂HF₃O₂*C₂₅H₂₈N₄O₆
Molecular Weight:594.544
Hs Code.:

(S)-1-{(S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carboxylic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid

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Chemical Property of (S)-1-{(S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carboxylic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid

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Technology Process of (S)-1-{(S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carboxylic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid

There total 1 articles about (S)-1-{(S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carboxylic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: C₃₁H₃₉N₃O₈

: 76-05-1
trifluoroacetic acid

: 80574-74-9
(S)-1-{(S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carboxylic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid

Guidance literature:: With dicyclohexyl-carbodiimide; Multistep reaction; 2.) CH₂Cl₂;
DOI:10.1016/S0040-4039(01)81989-4

Reference yield: 8.5%

: 80574-74-9
(S)-1-{(S)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionyl}-pyrrolidine-2-carboxylic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid

: 80585-13-3
C₁₉H₂₃N₃O₃

Guidance literature:: With sodium hydrogencarbonate; sodium carbonate; In 1,4-dioxane; for 3h; Ambient temperature;
DOI:10.1016/S0040-4039(01)81989-4