(1R,2S,3R,4R)-1-[4,6-Bis-((1R,2S,3R,4R)-1,2,3,4,5-pentahydroxy-pentyl)-[1,3,5]trithian-2-yl]-pentane-1,2,3,4,5-pentaol

Base Information

• Chemical Name: (1R,2S,3R,4R)-1-[4,6-Bis-((1R,2S,3R,4R)-1,2,3,4,5-pentahydroxy-pentyl)-[1,3,5]trithian-2-yl]-pentane-1,2,3,4,5-pentaol
• CAS No.: 136632-68-3
• Molecular Formula: C₁₈H₃₆O₁₅S₃
• Molecular Weight: 588.673
• Mol file: 136632-68-3.mol

Synonyms:

Chemical Property of (1R,2S,3R,4R)-1-[4,6-Bis-((1R,2S,3R,4R)-1,2,3,4,5-pentahydroxy-pentyl)-[1,3,5]trithian-2-yl]-pentane-1,2,3,4,5-pentaol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2S,3R,4R)-1-[4,6-Bis-((1R,2S,3R,4R)-1,2,3,4,5-pentahydroxy-pentyl)-[1,3,5]trithian-2-yl]-pentane-1,2,3,4,5-pentaol

There total 3 articles about (1R,2S,3R,4R)-1-[4,6-Bis-((1R,2S,3R,4R)-1,2,3,4,5-pentahydroxy-pentyl)-[1,3,5]trithian-2-yl]-pentane-1,2,3,4,5-pentaol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-Glucose (2280-44-6) → 1-thio-α,α-trehalose (17317-98-5,18977-84-9,68667-06-1,68778-86-9,68778-87-0,68778-88-1,108392-13-8,62853-32-1,80441-61-8) + 1-thio-β-D-glucopyranose (22566-82-1,23558-19-2,49858-49-3,63073-99-4,135891-42-8,7534-35-2) + (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-mercaptotetrahydro-2H-pyran-3,4,5-triol (63073-99-4) + (1R,2S,3R,4R)-1-[4,6-Bis-((1R,2S,3R,4R)-1,2,3,4,5-pentahydroxy-pentyl)-[1,3,5]trithian-2-yl]-pentane-1,2,3,4,5-pentaol (136632-68-3)

Guidance literature:

With hydrogen sulfide; In hydrogen fluoride; at 0 ℃; for 4h; Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/0008-6215(91)84116-V

Reference yield:

D-Glucose (2280-44-6) → 1-thio-α,β-trehalose (68778-86-9,80441-61-8) + 1-thio-α,α-trehalose (17317-98-5,18977-84-9,68667-06-1,68778-86-9,68778-87-0,68778-88-1,108392-13-8,62853-32-1,80441-61-8) + D-glycopyranosyl β-D-thioglucopyranoside (108392-13-8,80441-61-8) + (1R,2S,3R,4R)-1-[4,6-Bis-((1R,2S,3R,4R)-1,2,3,4,5-pentahydroxy-pentyl)-[1,3,5]trithian-2-yl]-pentane-1,2,3,4,5-pentaol (136632-68-3)

Guidance literature:

With hydrogen sulfide; In hydrogen fluoride; at 20 ℃; for 1h; Further byproducts given. Title compound not separated from byproducts;

DOI:10.1016/0008-6215(91)84116-V

Reference yield:

D-Glucose (2280-44-6) → 1-thio-α,β-trehalose (68778-86-9,80441-61-8) + 1-thio-α,α-trehalose (17317-98-5,18977-84-9,68667-06-1,68778-86-9,68778-87-0,68778-88-1,108392-13-8,62853-32-1,80441-61-8) + 1-thio-β-D-glucopyranose (22566-82-1,23558-19-2,49858-49-3,63073-99-4,135891-42-8,7534-35-2) + (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-mercaptotetrahydro-2H-pyran-3,4,5-triol (63073-99-4) + D-glycopyranosyl β-D-thioglucopyranoside (108392-13-8,80441-61-8) + (1R,2S,3R,4R)-1-[4,6-Bis-((1R,2S,3R,4R)-1,2,3,4,5-pentahydroxy-pentyl)-[1,3,5]trithian-2-yl]-pentane-1,2,3,4,5-pentaol (136632-68-3)

Guidance literature:

With hydrogen sulfide; In hydrogen fluoride; at 0 ℃; for 2.5h; Mechanism; Product distribution; other reaction temperatures and times;

DOI:10.1016/0008-6215(91)84116-V

upstream raw materials:

D-Glucose