(R)-(-)-Methadone-d₁₀ hydrochloride

Base Information

• Chemical Name: (R)-(-)-Methadone-d₁₀ hydrochloride
• CAS No.: 80024-94-8
• Molecular Formula: C₂₁H₂₇NO*ClH
• Molecular Weight: 355.833
• Mol file: 80024-94-8.mol

Synonyms:

Chemical Property of (R)-(-)-Methadone-d₁₀ hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-(-)-Methadone-d₁₀ hydrochloride

There total 8 articles about (R)-(-)-Methadone-d₁₀ hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzene-d6 (1076-43-3) → (S)-(+)-Methadone-d10 hydrochloride (80024-94-8,80024-95-9,80041-50-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) AlCl₃; 2.) H₂O

2: t-BuOK / dimethylsulfoxide; methanol / 17 h / Ambient temperature

4: 2.) aq. HCl

With hydrogenchloride; aluminium trichloride; potassium tert-butylate; water; In methanol; dimethyl sulfoxide;

Reference yield:

benzene-d6 (1076-43-3) → (R)-(-)-Methadone-d10 hydrochloride (80024-94-8,80024-95-9,80041-50-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) AlCl₃; 2.) H₂O

2: t-BuOK / dimethylsulfoxide; methanol / 17 h / Ambient temperature

4: 2.) aq. HCl

With hydrogenchloride; aluminium trichloride; potassium tert-butylate; water; In methanol; dimethyl sulfoxide;

Reference yield:

(2H10)benzophenone (22583-75-1) → (S)-(+)-Methadone-d10 hydrochloride (80024-94-8,80024-95-9,80041-50-5)

Guidance literature:

Multi-step reaction with 3 steps

1: t-BuOK / dimethylsulfoxide; methanol / 17 h / Ambient temperature

3: 2.) aq. HCl

With hydrogenchloride; potassium tert-butylate; In methanol; dimethyl sulfoxide;

upstream raw materials:

ethylmagnesium bromide

(S)-(+)-2,2-di-(2H₅-phenyl)-4-dimethylaminopentanenitrile

benzene-d6

(2H₁₀)benzophenone