Carbobenzyloxyglycylsarcosine benzyl ester

Base Information

Chemical Name:Carbobenzyloxyglycylsarcosine benzyl ester
CAS No.:148205-75-8
Molecular Formula:C₂₀H₂₂N₂O₅
Molecular Weight:370.405
Hs Code.:
European Community (EC) Number:667-934-4
NSC Number:169140

Synonyms:NSC169140;CARBOBENZYLOXYGLYCYLSARCOSINE BENZYL ESTER;AKOS024432471;NSC-169140

Suppliers and Price of Carbobenzyloxyglycylsarcosine benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Carbobenzyloxyglycylsarcosine benzyl ester

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:370.15287181
Heavy Atom Count:27
Complexity:485

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(CC(=O)OCC1=CC=CC=C1)C(=O)CNC(=O)OCC2=CC=CC=C2

Technology Process of Carbobenzyloxyglycylsarcosine benzyl ester

There total 1 articles about Carbobenzyloxyglycylsarcosine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1138-80-3
N-(Benzyloxycarbonyl)glycine

: 148205-75-8
Z-Gly-Sar-OBzl

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / dimethylformamide / 0.25 h / -10 °C

2: 68 percent / dimethylformamide

With triethylamine; In N,N-dimethyl-formamide;
DOI:10.1248/cpb.40.3253

Reference yield:

: 148205-75-8
Z-Gly-Sar-OBzl

: 148205-77-0
Z-Gly-Sar-Arg(NO₂)-Pro-OBzl

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / NH₂NH₂*H₂O / methanol

2: 1.) isoamyl nitrite, 7.4 N dioxane HCl, 2.) Et₃N / 1.) DMF, -10 deg C, 15 min, 2.) DMF, overnight

With hydrochloric acid dioxane; hydrazine hydrate; triethylamine; isopentyl nitrite; In methanol;
DOI:10.1248/cpb.40.3253