Technology Process of 1,2,3,4,9,9a-hexahydro-6,9a-di(p-methylphenyl)pyrimido<2,1-c><1,4>thiazine
There total 1 articles about 1,2,3,4,9,9a-hexahydro-6,9a-di(p-methylphenyl)pyrimido<2,1-c><1,4>thiazine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
ethanol; ethylene glycol;
Ambient temperature;
- Guidance literature:
-
With
HBr;
In
ethanol; benzene;
dropwise addn. of a soln. of ligand in dry benzene to a soln. of PdBr2 in abs. ethanol containing a few drops of HBr with constant stirring at room temp., pptn.; filtn., washing with abs. ethanol and dry benzene, drying in vacuo at 60°C, elem. anal.;
- Guidance literature:
-
With
HCl;
In
tetrahydrofuran; ethanol;
dropwise addn. of a soln. of ligand in THF to a soln. of PdCl2 in abs. ethanol containing a few drops of HCl with stirring, pptn., stirring for30 min; filtn., washing with THF and abs. ethanol, drying in vacuo at 60°C, elem. anal.;
