Technology Process of C29H25FN4O3
There total 8 articles about C29H25FN4O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
DOI:10.1016/j.cclet.2010.05.026
- Guidance literature:
-
Multi-step reaction with 7 steps
1: potassium hydroxide / water / 15 h / Reflux
2: sulfuric acid / 3 h / 70 °C
3: iodine; sodium hydroxide / methanol / 1 h / 20 °C
4: acetic acid / 80 °C
5: sodium carbonate / methanol / 3 h / 20 °C
6: methanol; lithium hydroxide / tetrahydrofuran / 16 h / 20 °C
7: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 20 °C
With
methanol; sulfuric acid; iodine; sodium carbonate; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; sodium hydroxide; lithium hydroxide;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.cclet.2010.05.026
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sulfuric acid / 3 h / 70 °C
2: iodine; sodium hydroxide / methanol / 1 h / 20 °C
3: acetic acid / 80 °C
4: sodium carbonate / methanol / 3 h / 20 °C
5: methanol; lithium hydroxide / tetrahydrofuran / 16 h / 20 °C
6: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 20 °C
With
methanol; sulfuric acid; iodine; sodium carbonate; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide; lithium hydroxide;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.cclet.2010.05.026