2-((2-(3-fluorobenzylthio)pyrimidin-4-yl)(allyl)amino)-N-tert-butylbutanamide

Base Information Edit

Chemical Name:2-((2-(3-fluorobenzylthio)pyrimidin-4-yl)(allyl)amino)-N-tert-butylbutanamide
CAS No.:1373521-33-5
Molecular Formula:C₂₂H₂₉FN₄OS
Molecular Weight:416.563
Hs Code.:
Mol file:1373521-33-5.mol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-((2-(3-fluorobenzylthio)pyrimidin-4-yl)(allyl)amino)-N-tert-butylbutanamide Edit

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Technology Process of 2-((2-(3-fluorobenzylthio)pyrimidin-4-yl)(allyl)amino)-N-tert-butylbutanamide

There total 2 articles about 2-((2-(3-fluorobenzylthio)pyrimidin-4-yl)(allyl)amino)-N-tert-butylbutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 456-42-8
m-fluorobenzyl chloride

: 1373521-33-5
2-((2-(3-fluorobenzylthio)pyrimidin-4-yl)(allyl)amino)-N-tert-butylbutanamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / water / 3 h / Reflux

2: methanol / Inert atmosphere; Reflux

With potassium carbonate; In methanol; water; 2: Ugi-Smiles coupling reaction;
DOI:10.1055/s-0031-1290347