chlorhydrate du (benzoyloxy-5 β-D-ribofuranosyl) thioformimidate de benzyle

Base Information

• Chemical Name: chlorhydrate du (benzoyloxy-5 β-D-ribofuranosyl) thioformimidate de benzyle
• CAS No.: 55628-57-4
• Molecular Formula: C₂₀H₂₁NO₅S*ClH
• Molecular Weight: 423.917
• Mol file: 55628-57-4.mol

Synonyms:

Chemical Property of chlorhydrate du (benzoyloxy-5 β-D-ribofuranosyl) thioformimidate de benzyle

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of chlorhydrate du (benzoyloxy-5 β-D-ribofuranosyl) thioformimidate de benzyle

There total 3 articles about chlorhydrate du (benzoyloxy-5 β-D-ribofuranosyl) thioformimidate de benzyle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

5-O-benzoyl-β-D-ribofuranosyl cyanide (30002-87-0) + phenylmethanethiol (100-53-8) → chlorhydrate du (benzoyloxy-5 β-D-ribofuranosyl) thioformimidate de benzyle (55628-57-4,55650-11-8,73068-55-0,80581-14-2)

Guidance literature:

With hydrogenchloride;

DOI:10.1002/jhet.5570260418

Reference yield:

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (6974-32-9) → chlorhydrate du (benzoyloxy-5 β-D-ribofuranosyl) thioformimidate de benzyle (55628-57-4,55650-11-8,73068-55-0,80581-14-2)

Guidance literature:

Multi-step reaction with 3 steps

1: SnCl₄

2: NH₃ / methanol

3: 70 percent / HCl

With hydrogenchloride; ammonia; tin(IV) chloride; In methanol;

DOI:10.1002/jhet.5570260418

Reference yield:

2,3,5-tri-O-benzoyl-β-D-ribofuranosyl-1-carbonitrile (23316-67-8) → chlorhydrate du (benzoyloxy-5 β-D-ribofuranosyl) thioformimidate de benzyle (55628-57-4,55650-11-8,73068-55-0,80581-14-2)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₃ / methanol

2: 70 percent / HCl

With hydrogenchloride; ammonia; In methanol;

DOI:10.1002/jhet.5570260418

upstream raw materials:

5-O-benzoyl-β-D-ribofuranosyl cyanide

phenylmethanethiol

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

2,3,5-tri-O-benzoyl-β-D-ribofuranosyl-1-carbonitrile

Downstream raw materials:

β-D-ribofuranosyl-2 benzyloxy-8 (1,2,4)triazolo<1,5-c>pyrimidine

benzyl 2,5-anhydro-6-O-benzoyl-D-allonodithioate