diethyl 1,20-eicosanedicarboxylate

Base Information

• Chemical Name: diethyl 1,20-eicosanedicarboxylate
• CAS No.: 26818-50-8
• Molecular Formula: C₂₆H₅₀O₄
• Molecular Weight: 426.681
• Mol file: 26818-50-8.mol

Synonyms:

Chemical Property of diethyl 1,20-eicosanedicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diethyl 1,20-eicosanedicarboxylate

There total 1 articles about diethyl 1,20-eicosanedicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,12-dodecadicarboxylic acid monoethyl ester (66003-63-2) + 5-acetoxypentanoic acid (26976-70-5) → 1,8-octanediyl diacetate (3992-48-1) + ethyl 15-acetoxypentadecanoate (66003-64-3) + diethyl 1,20-eicosanedicarboxylate (26818-50-8)

Guidance literature:

With ammonium carbonate; In water; at 50 - 55 ℃; for 3h; Yield given. Yields of byproduct given; electrolysis, platinium anode, 35.7 A/dm², 10-15 V;

Reference yield:

diethyl 1,20-eicosanedicarboxylate (26818-50-8) → 7-[(1S,2R)-2-((E)-(R)-3-Hydroxy-oct-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid 22-[bis-(4-methyl-benzyloxy)-phosphoryloxy]-docosyl ester

Guidance literature:

Multi-step reaction with 5 steps

1: 86 percent / lithium aluminum hydride / diethyl ether / 1 h / Heating

2: 87 percent / thionyl chloride; pyridine / 1 h / Heating

3: 71 percent / sodium iodide / acetone / 125 °C

4: 40.4 percent / dimethylformamide / 1 h / 20 °C

5: 35 percent / benzene / 5 h / Heating

With pyridine; lithium aluminium tetrahydride; thionyl chloride; sodium iodide; In diethyl ether; N,N-dimethyl-formamide; acetone; benzene;

DOI:10.1023/A:1013910404606

upstream raw materials:

1,12-dodecadicarboxylic acid monoethyl ester

5-acetoxypentanoic acid