r-1,trans-2(e),6(e)-triphenyl-4-phosphorinanone

Base Information

• Chemical Name: r-1,trans-2(e),6(e)-triphenyl-4-phosphorinanone
• CAS No.: 18355-89-0
• Molecular Formula: C₂₃H₂₁OP
• Molecular Weight: 344.393
• Mol file: 18355-89-0.mol

Synonyms:

Chemical Property of r-1,trans-2(e),6(e)-triphenyl-4-phosphorinanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of r-1,trans-2(e),6(e)-triphenyl-4-phosphorinanone

There total 4 articles about r-1,trans-2(e),6(e)-triphenyl-4-phosphorinanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,5-diphenyl-1,4-pentadiene-3-one (538-58-9) + phenylphosphane (638-21-1) → C23H21OP (1384105-62-7) + r-1,trans-2(e),6(e)-triphenyl-4-phosphorinanone (18355-89-0,76189-76-9,76189-77-0)

Guidance literature:

phenylphosphane; With C₂₈H₂₆N₂PPd⁽¹⁺⁾*ClO₄^(1-); In tetrahydrofuran; at 20 ℃; for 0.0833333h;

1,5-diphenyl-1,4-pentadiene-3-one; With triethylamine; In tetrahydrofuran; at -80 - 20 ℃; for 36h; optical yield given as %ee; enantioselective reaction;

DOI:10.1021/om300405h

Reference yield:

1,5-diphenyl-1,4-pentadiene-3-one (538-58-9) + phenylphosphane (638-21-1) → OC5H6P(C6H5)3 (76189-76-9) + r-1,trans-2(e),6(e)-triphenyl-4-phosphorinanone (18355-89-0,76189-76-9,76189-77-0)

Guidance literature:

phenylphosphane; With [(C₁₀H₆CH(CH₃)P(C₆H₅)2)Pd(NCCH₃)2]⁽¹⁺⁾*ClO₄^(1-)=[(C₁₀H₆CH(CH₃)P(C₆H₅)2)Pd(NCCH₃)2]ClO₄; In tetrahydrofuran; at 20 ℃; for 0.0833333h;

1,5-diphenyl-1,4-pentadiene-3-one; With triethylamine; In tetrahydrofuran; at -80 - 20 ℃; for 36h; optical yield given as %ee; enantioselective reaction;

DOI:10.1021/om300405h

Reference yield:

1,5-diphenyl-1,4-pentadiene-3-one (538-58-9) + phenylphosphane (638-21-1) → OC5H6P(C6H5)3 (76189-76-9) + C23H21OP (1384105-62-7) + r-1,trans-2(e),6(e)-triphenyl-4-phosphorinanone (18355-89-0,76189-76-9,76189-77-0)

Guidance literature:

phenylphosphane; With [(C₁₀H₆CH(CH₃)P(C₆H₅)2)Pd(NCCH₃)2]⁽¹⁺⁾*ClO₄^(1-)=[(C₁₀H₆CH(CH₃)P(C₆H₅)2)Pd(NCCH₃)2]ClO₄; In chloroform; at 20 ℃; for 0.0833333h;

1,5-diphenyl-1,4-pentadiene-3-one; With triethylamine; In chloroform; at -40 - 20 ℃; for 36h; optical yield given as %ee; enantioselective reaction;

DOI:10.1021/om300405h

upstream raw materials:

1,5-diphenyl-1,4-pentadiene-3-one

bis(hydroxymethyl)phenylphosphine

phenylphosphane

Downstream raw materials:

1,2,6-triphenyl-phosphinane