Technology Process of 2,2-bis(4(methylthio)phenyl)pent-4-penenitrile
There total 3 articles about 2,2-bis(4(methylthio)phenyl)pent-4-penenitrile which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2,2’-bis(4-(methylthio)phenyl)acetonitrile;
With
n-butyllithium; diisopropylamine;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.5h;
Inert atmosphere;
allyl iodid;
In
tetrahydrofuran; hexane;
at -78 - 23 ℃;
for 16h;
Inert atmosphere;
DOI:10.1002/adsc.201400317
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: molybdenum(V) chloride / dichloromethane / 0.25 h / 23 °C
1.2: 3 h / 23 °C
2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
2.2: 16 h / -78 - 23 °C / Inert atmosphere
With
n-butyllithium; molybdenum(V) chloride; diisopropylamine;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1002/adsc.201400317
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.42 h / -40 - 23 °C / Inert atmosphere
1.2: 0.5 h / 0 - 23 °C / Inert atmosphere
2.1: molybdenum(V) chloride / dichloromethane / 0.25 h / 23 °C
2.2: 3 h / 23 °C
3.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
3.2: 16 h / -78 - 23 °C / Inert atmosphere
With
n-butyllithium; molybdenum(V) chloride; diisopropylamine;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1002/adsc.201400317
