Technology Process of C20H19FN4O3
There total 3 articles about C20H19FN4O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 48 h / 20 °C
2: ammonium hydroxide / 1,4-dioxane / 14 h / 120 °C
3: copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine / tetrahydrofuran / 20 h / 45 °C
With
ammonium hydroxide; copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; di-isopropyl azodicarboxylate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane;
1: Mitsunobu reaction;
DOI:10.1016/j.bmcl.2011.09.089
- Guidance literature:
-
Multi-step reaction with 4 steps
1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / 3 h / 0 °C
2: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 48 h / 20 °C
3: ammonium hydroxide / 1,4-dioxane / 14 h / 120 °C
4: copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine / tetrahydrofuran / 20 h / 45 °C
With
ammonium hydroxide; copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; di-isopropyl azodicarboxylate; lithium tri-t-butoxyaluminum hydride; triethylamine; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane;
2: Mitsunobu reaction;
DOI:10.1016/j.bmcl.2011.09.089
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ammonium hydroxide / 1,4-dioxane / 14 h / 120 °C
2: copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine / tetrahydrofuran / 20 h / 45 °C
With
ammonium hydroxide; copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine;
In
tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.bmcl.2011.09.089