Technology Process of C19H18ClN5O2
There total 5 articles about C19H18ClN5O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C13H13N3O3;
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 20 ℃;
5-chloro-2-(methylamino)pyridine;
at 20 ℃;
DOI:10.1039/c2md20174g
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran / -78 - -60 °C
1.2: -78 - -60 °C
2.1: lithium hydroxide / water; methanol / 70 °C
3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 20 °C
3.2: 20 °C
With
n-butyllithium; oxalyl dichloride; N,N-dimethyl-formamide; lithium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1039/c2md20174g
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: L-proline; sodium carbonate; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate; sodium azide; copper(ll) sulfate pentahydrate / dimethyl sulfoxide; water / 65 °C
2.1: n-butyllithium / tetrahydrofuran / -78 - -60 °C
2.2: -78 - -60 °C
3.1: lithium hydroxide / water; methanol / 70 °C
4.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 20 °C
4.2: 20 °C
With
n-butyllithium; sodium azide; copper(ll) sulfate pentahydrate; oxalyl dichloride; sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydro-furan-3-olate; sodium carbonate; N,N-dimethyl-formamide; L-proline; lithium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1039/c2md20174g
