Technology Process of 2,2,3,3,3-pentafluoropropyl (4-methyl-1-phenylpentyl)sulfamate
There total 4 articles about 2,2,3,3,3-pentafluoropropyl (4-methyl-1-phenylpentyl)sulfamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
isohexylbenzene; 2,2,3,3,3-pentafluoropropyl sulfamate;
With
bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; magnesium oxide;
In
Isopropyl acetate;
for 0.0833333h;
Molecular sieve;
Sealed tube;
With
[bis(acetoxy)iodo]benzene;
In
Isopropyl acetate;
for 16h;
Sealed tube;
DOI:10.1021/ja5015508
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: palladium on activated charcoal; hydrogen / ethyl acetate / 3 h / Inert atmosphere
2.1: bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; magnesium oxide / Isopropyl acetate / 0.08 h / Molecular sieve; Sealed tube
2.2: 16 h / Sealed tube
With
bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; palladium on activated charcoal; hydrogen; magnesium oxide;
In
Isopropyl acetate; ethyl acetate;
DOI:10.1021/ja5015508
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium tert-butylate / toluene; tetrahydrofuran / 4 h / Inert atmosphere
1.2: 3 h / -78 - 20 °C / Inert atmosphere
2.1: palladium on activated charcoal; hydrogen / ethyl acetate / 3 h / Inert atmosphere
3.1: bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; magnesium oxide / Isopropyl acetate / 0.08 h / Molecular sieve; Sealed tube
3.2: 16 h / Sealed tube
With
bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; palladium on activated charcoal; potassium tert-butylate; hydrogen; magnesium oxide;
In
tetrahydrofuran; Isopropyl acetate; ethyl acetate; toluene;
1.1: |Wittig Olefination / 1.2: |Wittig Olefination;
DOI:10.1021/ja5015508
