Technology Process of C23H20Cl2(18)FN3O5
There total 9 articles about C23H20Cl2(18)FN3O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
dimethyl sulfoxide;
at 100 ℃;
for 0.0833333h;
Automated synthesizer;
DOI:10.1002/jlcr.1901
- Guidance literature:
-
Multi-step reaction with 5 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 °C / Inert atmosphere
2: dichloromethane / 0 - 20 °C / Inert atmosphere
3: sodium ethanolate / ethanol / 1 h / 20 °C / Inert atmosphere
4: palladium 10% on activated carbon; hydrogen / methanol / 60 °C / 750.08 Torr
5: sodium hydroxide / dimethyl sulfoxide / 0.08 h / 100 °C / Automated synthesizer
With
palladium 10% on activated carbon; hydrogen; sodium ethanolate; N-ethyl-N,N-diisopropylamine; sodium hydroxide;
In
methanol; ethanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1002/jlcr.1901
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: triethylamine / dichloromethane / 0.17 h / Inert atmosphere
1.2: 0.25 h / Inert atmosphere
2.1: sodium tris(acetoxy)borohydride / dichloromethane / 1.5 h / Inert atmosphere
3.1: dichloromethane / 0 - 20 °C / Inert atmosphere
4.1: sodium ethanolate / ethanol / 1 h / 20 °C / Inert atmosphere
5.1: palladium 10% on activated carbon; hydrogen / methanol / 60 °C / 750.08 Torr
6.1: sodium hydroxide / dimethyl sulfoxide / 0.08 h / 100 °C / Automated synthesizer
With
palladium 10% on activated carbon; hydrogen; sodium ethanolate; sodium tris(acetoxy)borohydride; triethylamine; sodium hydroxide;
In
methanol; ethanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1002/jlcr.1901
