C₁₇H₁₈ClFO

Base Information

• Chemical Name: C₁₇H₁₈ClFO
• CAS No.: 1611490-95-9
• Molecular Formula: C₁₇H₁₈ClFO
• Molecular Weight: 292.781
• Mol file: 1611490-95-9.mol

Synonyms:

Chemical Property of C₁₇H₁₈ClFO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₈ClFO

There total 2 articles about C₁₇H₁₈ClFO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-cyclohexylcyclopent-2-en-1-one (126457-89-4) → C17H18ClFO (1611490-95-9)

Guidance literature:

Multi-step reaction with 2 steps

1: iodine; pyridine / tetrachloromethane

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / toluene; ethanol / Reflux

With pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; iodine; sodium carbonate; In tetrachloromethane; ethanol; toluene; 2: |Suzuki Coupling;

DOI:10.1016/j.bmcl.2014.04.115

Reference yield:

3-cyclohexyl-2-iodo-2-cyclopenten-1-one (890304-67-3) + 3-chloro-4-fluorophenylboronic acid (144432-85-9) → C17H18ClFO (1611490-95-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; toluene; Reflux;

DOI:10.1016/j.bmcl.2014.04.115

Reference yield:

C17H18ClFO (1611490-95-9) → 3-cyclohexyl-2-(3-chloro-4-fluorophenyl)-2-cyclopenten-1-one oxime

Guidance literature:

With pyridine; hydroxylamine hydrochloride;

DOI:10.1016/j.bmcl.2014.04.115

upstream raw materials:

3-cyclohexylcyclopent-2-en-1-one

3-cyclohexyl-2-iodo-2-cyclopenten-1-one

3-chloro-4-fluorophenylboronic acid