[Cyclopropyl(phenyl)methyl](methyl)amine

Base Information

• Chemical Name: [Cyclopropyl(phenyl)methyl](methyl)amine
• CAS No.: 178177-09-8
• Molecular Formula: C₁₁H₁₅N
• Molecular Weight: 161.247
• European Community (EC) Number: 822-555-5
• Nikkaji Number: J764.372A
• Mol file: 178177-09-8.mol

Synonyms:[cyclopropyl(phenyl)methyl](methyl)amine;178177-09-8;1-cyclopropyl-N-methyl-1-phenylmethanamine;SCHEMBL10063384;AKOS009515010;AM100393;alpha-Cyclopropyl-N-methylbenzenemethanamine;CS-0262424;EN300-82530

Chemical Property of [Cyclopropyl(phenyl)methyl](methyl)amine

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 161.120449483
• Heavy Atom Count: 12
• Complexity: 134

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CNC(C1CC1)C2=CC=CC=C2

Technology Process of [Cyclopropyl(phenyl)methyl](methyl)amine

There total 1 articles about [Cyclopropyl(phenyl)methyl](methyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

phenylmagnesium bromide (100-58-3) + cyclopropylcarboxaldehyde N-methylaldimine → (Cyclopropyl-phenyl-methyl)-methyl-amine (178177-09-8)

Guidance literature:

In diethyl ether;

DOI:10.1055/s-1995-4131

Reference yield: 80.0%

4-methoxy-5-(4-methoxyphenoxy)cyclohexa-3,5-diene-1,2-dione (99814-64-9) + (Cyclopropyl-phenyl-methyl)-methyl-amine (178177-09-8) → 4-[(Cyclopropyl-phenyl-methyl)-methyl-amino]-5-methoxy-[1,2]benzoquinone (179805-59-5) + 4-[(Cyclopropyl-phenyl-methyl)-methyl-amino]-5-(4-methoxy-phenoxy)-[1,2]benzoquinone

Guidance literature:

In water; acetonitrile; Ambient temperature;

DOI:10.1055/s-1995-4131

Reference yield:

4-methoxy-5-(4-methoxyphenoxy)cyclohexa-3,5-diene-1,2-dione (99814-64-9) + (Cyclopropyl-phenyl-methyl)-methyl-amine (178177-09-8) → 4-[(Cyclopropyl-phenyl-methyl)-methyl-amino]-5-methoxy-[1,2]benzoquinone (179805-59-5)

Guidance literature:

In water; acetonitrile; Ambient temperature;

DOI:10.1016/0040-4020(96)00430-9

upstream raw materials:

phenylmagnesium bromide

Downstream raw materials:

4-[(Cyclopropyl-phenyl-methyl)-methyl-amino]-5-methoxy-[1,2]benzoquinone