Technology Process of 9-benzyloxy-4-(3,4-methylenedioxyphenyl)-5,6,7-trimethoxy-3a,4,9,9a-tetrahydronaphtho<2,3-c>furan-1(3H)-one
There total 6 articles about 9-benzyloxy-4-(3,4-methylenedioxyphenyl)-5,6,7-trimethoxy-3a,4,9,9a-tetrahydronaphtho<2,3-c>furan-1(3H)-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
boron trifluoride diethyl etherate;
In
dichloromethane;
for 0.5h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: N-bromosuccinimide (NBS), peroxyde de benzoyle (POB) / CCl4 / 1.75 h / Heating
2: 51 percent / H2O / tetrahydrofuran / 48 h / Ambient temperature
3: 58 percent / KOH / dimethylsulfoxide / 0.67 h
4: 90 percent / hexamethyldisilylamidure de lithium (LHMDS) / benzene; hexane / 0.08 h / Ambient temperature
5: 56 percent / BF3*Et2O / CH2Cl2 / 0.5 h / Ambient temperature
With
potassium hydroxide; N-Bromosuccinimide; Perbenzoic acid; boron trifluoride diethyl etherate; water; lithium hexamethyldisilazane;
In
tetrahydrofuran; tetrachloromethane; hexane; dichloromethane; dimethyl sulfoxide; benzene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 51 percent / H2O / tetrahydrofuran / 48 h / Ambient temperature
2: 58 percent / KOH / dimethylsulfoxide / 0.67 h
3: 90 percent / hexamethyldisilylamidure de lithium (LHMDS) / benzene; hexane / 0.08 h / Ambient temperature
4: 56 percent / BF3*Et2O / CH2Cl2 / 0.5 h / Ambient temperature
With
potassium hydroxide; boron trifluoride diethyl etherate; water; lithium hexamethyldisilazane;
In
tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; benzene;