3-(TrifluoroMethoxy)-2-pyridineMethanaMine

Base Information

• Chemical Name: 3-(TrifluoroMethoxy)-2-pyridineMethanaMine
• CAS No.: 1206977-79-8
• Molecular Formula: C₇H₇F₃N₂O
• Molecular Weight: 192.141
• Mol file: 1206977-79-8.mol

Synonyms:

Chemical Property of 3-(TrifluoroMethoxy)-2-pyridineMethanaMine

Chemical Property:

Purity/Quality:

2-(Aminomethyl)-3-(trifluoromethoxy)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(TrifluoroMethoxy)-2-pyridineMethanaMine

There total 2 articles about 3-(TrifluoroMethoxy)-2-pyridineMethanaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(trifluoromethoxy)pyridine-2-carbonitrile → 1-[3-(trifluoromethoxy)pyridin-2-yl]methanamine (1206977-79-8)

Guidance literature:

With ammonia; hydrogen; In methanol; water; at 20 ℃; for 2h; Inert atmosphere;

Reference yield:

2-bromo-3-(trifluoromethoxy)pyridine (1206978-11-1) → 1-[3-(trifluoromethoxy)pyridin-2-yl]methanamine (1206977-79-8)

Guidance literature:

Multi-step reaction with 2 steps

1: t-BuXantPhos-Pd-G₃ / water; tetrahydrofuran / 2 h / 80 °C / Inert atmosphere

2: hydrogen; ammonia / water; methanol / 2 h / 20 °C / Inert atmosphere

With ammonia; hydrogen; In tetrahydrofuran; methanol; water;

upstream raw materials:

2-bromo-3-(trifluoromethoxy)pyridine

Refernces