N-(4-Fluorophenyl)-3-hydroxypropanamide

Base Information

Chemical Name:N-(4-Fluorophenyl)-3-hydroxypropanamide
CAS No.:38470-23-4
Molecular Formula:C₉H₁₀FNO₂
Molecular Weight:183.182
Hs Code.:
DSSTox Substance ID:DTXSID501277922

Synonyms:N-(4-Fluorophenyl)-3-hydroxypropanamide;SCHEMBL14816847;DTXSID501277922;38470-23-4

Suppliers and Price of N-(4-Fluorophenyl)-3-hydroxypropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(4-Fluorophenyl)-3-hydroxypropanamide

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:183.06955672
Heavy Atom Count:13
Complexity:167

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)CCO)F

Technology Process of N-(4-Fluorophenyl)-3-hydroxypropanamide

There total 4 articles about N-(4-Fluorophenyl)-3-hydroxypropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 136005-64-6
N-cyclopropyl-4-fluorobenzenamine

: 38470-23-4
N-(4-fluorophenyl)-3-hydroxypropanamide

Guidance literature:: With air; for 66h; Irradiation; Neat (no solvent);
DOI:10.1080/00397911.2010.545166

Reference yield:

: 371-40-4
4-fluoroaniline

: 38470-23-4
N-(4-fluorophenyl)-3-hydroxypropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: methanol; acetic acid / Reflux

2: sodium tetrahydroborate; aluminum (III) chloride / tetrahydrofuran / 0 - 50 °C

3: air / 66 h / Irradiation; Neat (no solvent)

With aluminum (III) chloride; sodium tetrahydroborate; In tetrahydrofuran; methanol; acetic acid;
DOI:10.1080/00397911.2010.545166

Reference yield:

: C₁₁H₁₄FNO

: 38470-23-4
N-(4-fluorophenyl)-3-hydroxypropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate; aluminum (III) chloride / tetrahydrofuran / 0 - 50 °C

2: air / 66 h / Irradiation; Neat (no solvent)

With aluminum (III) chloride; sodium tetrahydroborate; In tetrahydrofuran;
DOI:10.1080/00397911.2010.545166