Technology Process of C20H15F2N3O3
There total 6 articles about C20H15F2N3O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium phosphate / dimethyl sulfoxide / 0.5 h / 100 °C
2: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 5 h / Reflux
3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 21 h / 20 °C
4: methanol / 0.25 h / 20 °C
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
1,4-dioxane; methanol; dichloromethane; dimethyl sulfoxide;
2: Suzuki-Miyaura coupling;
DOI:10.1055/s-0031-1290079
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -40 °C / Inert atmosphere
1.2: 1.5 h / -40 - 20 °C
1.3: 0.33 h / 5 - 20 °C
2.1: potassium phosphate / dimethyl sulfoxide / 0.5 h / 100 °C
3.1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 5 h / Reflux
4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 21 h / 20 °C
5.1: methanol / 0.25 h / 20 °C
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide;
In
tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; dimethyl sulfoxide;
3.1: Suzuki-Miyaura coupling;
DOI:10.1055/s-0031-1290079
