C₂₁H₁₈N₂O₃

Base Information

• Chemical Name: C₂₁H₁₈N₂O₃
• CAS No.: 1310720-68-3
• Molecular Formula: C₂₁H₁₈N₂O₃
• Molecular Weight: 346.386
• Mol file: 1310720-68-3.mol

Synonyms:

Chemical Property of C₂₁H₁₈N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₁₈N₂O₃

There total 1 articles about C₂₁H₁₈N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Bromodiphenyl ether (101-55-3) + 2-formyl-5-methoxy-4-azaindole (17288-50-5) → C21H18N2O3 (1310720-68-3)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -10 ℃; for 2h;

DOI:10.1016/j.bmcl.2011.01.012

Reference yield:

C21H18N2O3 (1310720-68-3) → C21H16N2O3 (1310721-06-2)

Guidance literature:

With manganese(IV) oxide; In chloroform; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2011.01.012

Reference yield:

C21H18N2O3 (1310720-68-3) → C20H14N2O3 (1282035-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: manganese(IV) oxide / chloroform / 1 h / 20 °C

2: boron tribromide / dichloromethane / 6 h / 20 °C

With manganese(IV) oxide; boron tribromide; In dichloromethane; chloroform;

DOI:10.1016/j.bmcl.2011.01.012

upstream raw materials:

4-Bromodiphenyl ether

2-formyl-5-methoxy-4-azaindole

Downstream raw materials:

C₂₀H₁₄N₂O₃

C₂₁H₁₆N₂O₃