Technology Process of C20H16F3N3O2
There total 5 articles about C20H16F3N3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
toluene;
at 80 ℃;
for 1.5h;
Inert atmosphere;
DOI:10.1021/jm301708u
- Guidance literature:
-
Multi-step reaction with 4 steps
1: caesium carbonate / N,N-dimethyl-formamide / 14 h / 70 - 80 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / methanol; tetrahydrofuran / 760.05 Torr / Inert atmosphere
3: trichloromethyl chloroformate; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 0.75 h / 0 °C / Inert atmosphere
4: toluene / 1.5 h / 80 °C / Inert atmosphere
With
palladium 10% on activated carbon; hydrogen; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; caesium carbonate; trichloromethyl chloroformate;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm301708u
- Guidance literature:
-
Multi-step reaction with 4 steps
1: caesium carbonate / N,N-dimethyl-formamide / 14 h / 70 - 80 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / methanol; tetrahydrofuran / 760.05 Torr / Inert atmosphere
3: trichloromethyl chloroformate; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 0.75 h / 0 °C / Inert atmosphere
4: toluene / 1.5 h / 80 °C / Inert atmosphere
With
palladium 10% on activated carbon; hydrogen; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; caesium carbonate; trichloromethyl chloroformate;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm301708u