CPI-1205

Base Information

Chemical Name:CPI-1205
CAS No.:1621862-70-1
Molecular Formula:C₂₇H₃₃F₃N₄O₃
Molecular Weight:518.579
Hs Code.:
Mol file:1621862-70-1.mol

Synonyms:

Suppliers and Price of CPI-1205

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indole-3-carboxamide 95%+
1g
$ 9280.00

ApexBio Technology
CPI-1205
50mg
$ 1733.00

Total 12 raw suppliers

Chemical Property of CPI-1205

Chemical Property:

Boiling Point:692.5±55.0 °C(Predicted)
PKA:11.01±0.10(Predicted)
Density:1.31±0.1 g/cm3(Predicted)
Solubility.:Soluble in DMSO

Purity/Quality:

99%, ^*data from raw suppliers

N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indole-3-carboxamide 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of CPI-1205

There total 27 articles about CPI-1205 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1438382-15-0
3-(aminomethyl)-4-methoxy-6-methylpyridin-2(1H)-one

: (R)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxylic acid

: 1621862-70-1
CPI-1205

Guidance literature:: (R)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxylic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 60 ℃; for 4.5h; Large scale;

3-(aminomethyl)-4-methoxy-6-methylpyridin-2(1H)-one; In tetrahydrofuran; at 60 ℃; for 20h; Large scale;

Reference yield:

: 1438382-15-0
3-(aminomethyl)-4-methoxy-6-methylpyridin-2(1H)-one

: (R)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxylic acid

: 1621862-70-1
CPI-1205

Guidance literature:: (R)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxylic acid; With 1,1′-carbonyldiimidazole; In tetrahydrofuran; at 60 ℃; for 1h; Large scale;

3-(aminomethyl)-4-methoxy-6-methylpyridin-2(1H)-one; In tetrahydrofuran; isopropyl alcohol; at 60 ℃; Large scale;

Reference yield:

: 1450662-05-1
2,4-dimethoxy-6-methylnicotinonitrile

: 1621862-70-1
CPI-1205

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; hydrogen / tetrahydrofuran; methanol / 20 °C

2: hydrogenchloride / water / 4.5 h / Reflux

3: sodium methylate / methanol; dichloromethane / 1 h / 20 °C

4: tetrahydrofuran / 24 h / Reflux

With hydrogenchloride; hydrogen; sodium methylate; triethylamine; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1021/acs.jmedchem.6b01315