Ethyl 3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate

Base Information

Chemical Name:Ethyl 3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate
CAS No.:147992-86-7
Molecular Formula:C₁₂H₁₅N₃O₂S
Molecular Weight:265.336
Hs Code.:
DSSTox Substance ID:DTXSID90358148
Nikkaji Number:J541.714G
Wikidata:Q82138482
Mol file:147992-86-7.mol

Synonyms:ethyl 3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate;147992-86-7;Ethyl 3-amino-4-(dimethylamino)thieno-[2,3-b]pyridine-2-carboxylate;CBMicro_042061;DTXSID90358148;HMS1612F08;MFCD01105700;STK526076;AKOS001642899;BIM-0042137.P001;9M-048;AB00102194-01;SR-01000484196;J-520844;SR-01000484196-1;ethyl3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate

Suppliers and Price of Ethyl 3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 3-amino-4-(dimethylamino)thieno-[2,3-b]pyridine-2-carboxylate >95%
500mg
$ 599.00

Matrix Scientific
Ethyl 3-amino-4-(dimethylamino)thieno-[2,3-b]pyridine-2-carboxylate >95%
1g
$ 756.00

Crysdot
Ethyl3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate 95+%
1g
$ 749.00

American Custom Chemicals Corporation
ETHYL 3-AMINO-4-(DIMETHYLAMINO)THIENO[2,3-B]PYRIDINE-2-CARBOXYLATE 95.00%
5MG
$ 502.03

Total 3 raw suppliers

Chemical Property of Ethyl 3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate

Chemical Property:

Melting Point:96-98°
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:265.08849790
Heavy Atom Count:18
Complexity:314

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl 3-amino-4-(dimethylamino)thieno-[2,3-b]pyridine-2-carboxylate >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=C(C2=C(C=CN=C2S1)N(C)C)N

Technology Process of Ethyl 3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate

There total 3 articles about Ethyl 3-amino-4-(dimethylamino)thieno[2,3-b]pyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: (3-Cyano-4-dimethylamino-pyridin-2-ylsulfanyl)-acetic acid ethyl ester

: 147992-86-7
3-Amino-4-dimethylamino-thieno[2,3-b]pyridine-2-carboxylic acid ethyl ester

Guidance literature:: With sodium ethanolate; In ethanol; Heating;
DOI:10.1007/BF00767663

Reference yield:

: 147992-80-1
2-chloro-4-(dimethylamino)nicotinonitrile

: 147992-86-7
3-Amino-4-dimethylamino-thieno[2,3-b]pyridine-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / thiourea / toluene / 4 h / Heating

2: 1.) KOH / 1.) water, DMF, 2.) water, DMF, from 5 deg C to 7 deg C, 15 min

3: 86 percent / NaOEt / ethanol / Heating

With potassium hydroxide; sodium ethanolate; thiourea; In ethanol; toluene;
DOI:10.1007/BF00767663

Reference yield:

: 147992-79-8
4-(dimethylamino)-2-thioxo-1,2-dihydropyridine-3-carbonitrile

: 147992-86-7
3-Amino-4-dimethylamino-thieno[2,3-b]pyridine-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) KOH / 1.) water, DMF, 2.) water, DMF, from 5 deg C to 7 deg C, 15 min

2: 86 percent / NaOEt / ethanol / Heating

With potassium hydroxide; sodium ethanolate; In ethanol;
DOI:10.1007/BF00767663