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147992-80-1

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147992-80-1 Usage

General Description

2-chloro-4-(dimethylamino)pyridine-3-carbonitrile is a chemical compound with the molecular formula C8H7ClN4. It is a pyridine derivative and contains a chlorine atom, a dimethylamino group, and a carbonitrile group attached to the pyridine ring. 2-chloro-4-(dimethylamino)pyridine-3-carbonitrile is commonly used as a building block in organic synthesis, particularly in the pharmaceutical industry for the production of various drugs and compounds. It is known for its ability to act as a nucleophilic catalyst and for its use in the synthesis of diverse heterocyclic compounds. This chemical is important in medicinal chemistry and offers a wide range of applications in the development of pharmaceuticals and other biologically active molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 147992-80-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,9,9 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 147992-80:
(8*1)+(7*4)+(6*7)+(5*9)+(4*9)+(3*2)+(2*8)+(1*0)=181
181 % 10 = 1
So 147992-80-1 is a valid CAS Registry Number.

147992-80-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-4-(dimethylamino)pyridine-3-carbonitrile

1.2 Other means of identification

Product number -
Other names 3-Pyridinecarbonitrile,2-chloro-4-(dimethylamino)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147992-80-1 SDS

147992-80-1Relevant articles and documents

FUSED TRICYCLIC MGLUR1 ANTAGONISTS AS THERAPEUTIC AGENTS

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Page/Page column 45; 48, (2010/11/26)

In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J3, X, Z, and R1-R4 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, part

ANTAGONISTS OF THE MGLU RECEPTOR AND USES THEREOF

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Page/Page column 30-31, (2008/06/13)

The present invention discloses compounds of general formula (I) wherein X1-X4 and R1-R3 are as defined in the description. The present invention also discloses methods of treatment for pain, neurodegeneration and convulsive states in a host mammal in need thereof, and pharmaceutical compositions including those compounds.

Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists

Zheng, Guo Zhu,Bhatia, Pramila,Daanen, Jerome,Kolasa, Teodozyj,Patel, Meena,Latshaw, Steven,El Kouhen, Odile F.,Chang, Renjie,Uchic, Marie E.,Miller, Loan,Nakane, Masaki,Lehto, Sonya G.,Honore, Marie P.,Moreland, Robert B.,Brioni, Jorge D.,Stewart, Andrew O.

, p. 7374 - 7388 (2007/10/03)

SAR (structure-activity relationship) studies of triazafluorenone derivatives as potent mGluR1 antagonists are described. The triazafluorenone derivatives are non-amino acid derivatives and noncompetitive mGluR1 antagonists that bind at a putative alloste

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